Topical compositions for the treatment of dermatological disorders
AssigneeEvologie LLC
InventorsGary I. Weinberger, H. Robert Nagel, Richard A. Browm
Life of this patent
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Abstract
The present invention relates to pharmaceutical compositions and methods useful for the treatment of dermatological disorders, and in particular acne vulgaris and skin pigmentation disorders. Pharmaceutical compositions comprising one or more arginine, salicylic acid and/or azelaic acid that are useful for the treatment of dermatological diseases and the symptoms and underlying causes of such dermatological diseases are also disclosed.
Claims31
A stable topical pharmaceutical composition comprising a tripartite complex, wherein the tripartite complex comprises L-arginine, azelaic acid and salicylic acid.
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A method of treating a dermatological disorder, wherein the method comprises topically administering to a subject affected with the dermatological disorder a pharmaceutical composition comprising an emulsion, wherein the emulsion comprises an aqueous phase and an oil phase, wherein the emulsion comprises one or more of an L-arginate salt of salicylic acid and an L-arginate salt of azelaic acid, wherein the one or more of an L-arginate salt of salicylic acid and an L-arginate salt of azelaic acid is solubilized in the aqueous phase, and wherein the emulsion comprises one or more alkyl esters of L-arginine.
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A pharmaceutical composition comprising a tripartite complex, wherein the tripartite complex has a structure of formula (II):
- wherein x, y and z are each any positive integer.
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Dependencies are inferred from the claim text.