Method for the treatment and prevention of Alzheimer's disease and central nervous system dysfunction
OwnerSteven Lehrerinventor
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Abstract
Intranasal insulin is beneficial for the treatment of Alzheimer's disease and other neurologic disorders. But commercial insulin preparations use metacresol, phenol, and other preservatives for chemical stabilization. Metacresol in particular has multiple toxic effects when administered long term, especially intranasal. These effects include rhinitis and nosebleeds. The present invention teaches the use of intranasal insulin not preserved with meta-cresol, phenol or other excipients for the treatment of Alzheimer's disease and other neurologic disorders.
Claims7
A method of achieving a therapeutically effective brain level of insulin comprising administering a dose of a pharmaceutical formulation of insulin or an analogue thereof into a single nostril or both nostrils.
Use according to claim ,1 wherein the insulin in the pharmaceutical preparation is in the form of a dry powder or dissolved in water.
Dependencies are inferred from the claim text.