Method for detecting pancreatic cancer
AssigneeToray Industries, Inc.
InventorsTakayoshi Ido, Fumiyoshi Okano
Life of this patent
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Abstract
This invention relates to a method for detecting pancreatic cancer using novel tumor markers. Specifically, the invention provides a method for detecting pancreatic cancer comprising measuring the presence or an amount of a polypeptide having an reactivity of binding via an antigen-antibody reaction to an antibody against CAPRIN-1 protein in a sample separated from a subject, and to a reagent or kit for detecting pancreatic cancer comprising a CAPRIN-1 protein or a fragment thereof, an antibody against the same, or a polynucleotide encoding the same.
Claims23
A method for detecting pancreatic cancer, comprising measuring the presence or an amount of a polypeptide having a reactivity of specifically binding to an antibody against a CAPRIN-1 protein via an antigen-antibody reaction, or the presence or an amount of a nucleic acid encoding the polypeptide, in a sample separated from a subject.
A reagent or kit for detecting pancreatic cancer, comprising one or more polypeptides having a reactivity of binding via an antigen-antibody reaction to an antibody induced against a CAPRIN-1 protein in the body of a subject.
A reagent or kit for detecting pancreatic cancer, comprising one or more antibodies that undergo an antigen-antibody reaction with a polypeptide having a reactivity of binding, via an antigen-antibody reaction, to an antibody against a CAPRIN-1 protein and produced in the body of a subject or to an antigen-binding fragment of the antibody.
A reagent or kit for detecting pancreatic cancer, comprising one or more polynucleotides that specifically hybridize to a partial sequence comprising at least 15 to 19 nucleotides or at least 20 to 30 nucleotides in the nucleotide sequence represented by any of the odd-numbered SEQ ID NOs:
- 1 to 29 and encoding a CAPRIN-1 protein or in a sequence complementary to the nucleotide sequence.
Dependencies are inferred from the claim text.