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US 2014/0179022 A1Published application
Rotating shielded magnetic actuator
AssigneeLuminex Corporation
InventorsEric SMITH, Adam Schilffarth
Life of this patent
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Abstract
Magnetic actuators comprising at least one shielded rotatable magnet are presented. Systems comprising such magnetic actuators and methods for using such magnetic actuators to isolate magnetic particles in a fluid are also presented.
Claims21
A magnetic actuator configured to isolate particles in a fluid assay, the magnetic actuator comprising:
- a first shielded magnet comprising a first shield coupled to and covering a portion of a first permanent magnet, where the first shielded magnet has a thickness, a length, and a first axis of rotation;
- a motor coupled to the first shielded magnet and configured to rotate the first shielded magnet about the axis of rotation;
- and
- a lateral support member configured to support the first shielded magnet and the motor.
1 more element
A magnetic actuator configured to isolate particles in a fluid assay, the magnetic actuator comprising:
- a first pair of shielded magnets rotatable together, each shielded magnet comprising a shield coupled to and covering at least a portion of a permanent magnet, where each shielded magnet has a thickness, a length, and an axis of rotation;
- a first motor coupled to the first pair of shielded magnets through a gearset and configured to rotate the first pair of shielded magnets about their respective axes of rotation;
- a second pair of shielded magnets rotatable together, each shielded magnet comprising a shield coupled to and covering a portion of a permanent magnet, where each shielded magnet has a thickness, a length, and an axis of rotation;
- and
- a second motor coupled to the second pair of shielded magnets through a gearset and configured to rotate the second pair of shielded magnets about their respective axes of rotation.
2 more elements
A system configured to isolate particles in a fluid assay comprising:
- a chassis;
- a magnetic actuator coupled to the chassis, the magnetic actuator having rotatable shielded magnets;
- a tub coupled to the chassis;
- and
- a well plate coupled to the tub and comprising a plurality of wells arranged in columns and rows;
- where the tub is configured to support the well plate such that each shielded magnet is adjacent to at least one column of wells.
3 more elements
A method for collecting a sample of magnetic particles from a liquid, comprising:
- obtaining a system comprising:
- a chassis;
- a magnetic actuator coupled to the chassis, the magnetic actuator having rotatable shielded magnets a tub coupled to the chassis;
- and
- a well plate coupled to the tub and comprising a plurality of wells arranged in columns and rows;
- where the tub is configured to support the well plate such that each shielded magnet is adjacent to at least one column of wells;
- obtaining a first suspension comprising a plurality of magnetic particles suspended in a first liquid;
- introducing a volume of the first suspension into at least one well;
- adjusting the shielded magnets to a first position such that a magnetic force is exerted on at least one column of wells;
- forming a pellet of magnetic particles in at least one well;
- and
- aspirating a portion of the first liquid from at least one well.
9 more elements
Dependencies are inferred from the claim text.