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US 2014/0179010 A1Published application
Methods of detecting reverse triiodothyronine by mass spectrometry
AssigneeQuest Diagnostics Investments Incorporated
InventorsJ. Fred BANKS, Peter P. CHOU, Noriya M. MATT
Life of this patent
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Abstract
Provided are methods for determining the amount of reverse T3 in a sample using mass spectrometry. The methods generally involve ionizing reverse T3 in a sample and detecting and quantifying the amount of the ion to determine the amount of reverse T3 in the sample.
Claims18
A method for determining the amount of reverse triiodothyronine (rT3) in a sample by mass spectrometry, said method comprising:
- a. ionizing rT3 from the sample to generate one or more rT3 ions detectable by mass spectrometry;
- b. determining the amount of one or more rT3 ions by mass spectrometry;
- and
- c. determining the amount of rT3 in the body fluid sample from the amount of said rT3 ions determined in (b).
1 more element
A kit for a reverse triiodothyronine (rT3) quantitation assay, the kit comprising an internal standard suitable for mass spectrometry, packaging material, and instructions.
Dependencies are inferred from the claim text.