Genetically engineered microbial strains including chlorella protothecoides lipid pathway genes
AssigneeSolazyme, Inc.
InventorsScott Franklin, Shane Brubaker, George N. Rudenko, Riyaz Bhat, Matthew Shoa-Azar, Aravind Somanchi, Aren Ewing
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Abstract
Genetically engineered microbial, e.g., Chlorella protothecoides, cells producing microbial oils are useful as a food additive and a source of renewable fuels and industrial chemicals. Lipid biosynthesis genes for Auxenochlorella protethecoides are disclosed that are useful for increasing lipid production and altering fatty acid and triacylglycerol profiles in recombinant microrganisms including cells of the genus Auxenochlorella or Prototheca.
Claims21
An expression cassette or recombinant cell comprising a coding sequence that encodes a Chlorella protothecoides lipid biosynthesis protein.
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A genetically engineered Chlorella protothecoides cell comprising one or more exogenous genes codon optimized for expression in the plastid of the Chlorella protothecoides cell.
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