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US 2014/0178893 A1Published application
Non-invasive enzyme screen for tissue remodelling-associated conditions
AssigneeChildren's Medical Center Corporation
InventorsMarsha A. Moses, Michael R. Freeman, Dmitri Wiederschain
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Abstract
Methods and kits for diagnosing the presence of and prognosing the appearance of tissue remodelling-associated conditions, involving the presence of enzymes in a biological sample, are disclosed. In particular, the method pertains to diagnosing the presence of or prognosing appearance of cancer, metastatic cancer, and obstructive and degenerative conditions.
Claims16
A non-invasive method for facilitating the detection of a tissue remodeling-associated condition in a subject, comprising:
- i. obtaining a urine sample from a subject;
- and
- ii. detecting a matrix metalloproteinase in the urine sample;
- wherein the presence of the matrix metalloproteinase (MMP) facilitates the detection of the condition in a subject.
1 more element
Dependencies are inferred from the claim text.