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US 2014/0178854 A1Published application
Antisera assays for mlv related viruses in humans and other mammals
AssigneeTocagen Inc.
InventorsDouglas J. Jolly, Carlos Ibanez, Omar D. Perez, Harry E. Gruber
Life of this patent
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Abstract
The disclosure provide cell lines and methods for the production of vectors and viral particles useful in diagnostics and therapeutics.
Claims29
A method for detecting anti-viral antibodies for amphotropic MLV or MLV like virus in a biological sample compromising
- a) incubating a biological sample with a capture reagent immobilized on a solid support to bind multiple anti-viral antibodies to amphotropic MLV to the capture reagent, wherein the capture reagent comprises a purified viral preparation;
- b) detecting bound anti-viral antibodies bound to immobilized capture reagent by contacting the bound anti-viral antibodies with a labeled detecting secondary agent.
An immunoassay kit for detecting anti-viral antibodies comprising:
- a) an antibody that specifically binds to amphotropic envelop as a control;
- b) a capture reagent comprising a purified viral particle.
Dependencies are inferred from the claim text.