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US 2014/0178470 A1Published application
Dispersible tablet
AssigneeAzanta A/S
InventorsNilesh Tanhaji Dumbre, Mahesh Mohanrao Bhadgale, Vardhaman Chandrakant Bafna
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Abstract
The present invention relates to a tablet comprising Nimorazole. In particular, the invention concerns a pharmaceutical composition or a tablet comprising Nimorazole or a pharmaceutically acceptable salt, for dispersion in water and administration via a tube to a patient with swallowing difficulties.
Claims22
A solid pharmaceutical composition dosage form comprising:
- i) nimorazole or a pharmaceutically acceptable salt thereof;
- ii) a disintegrant;
- iii) a coating sufficient to substantially mask the taste of nimorazole;
- and
- iv) optionally one or more additional excipients;
- wherein said solid pharmaceutical composition dosage form allows administration both by directly swallowing the unaltered dosage form and by allowing the dosage form to disintegrate or disperse in an aqueous medium and to be administered to a patient via a feeding tube, and wherein one or more of said dosage forms are dispersible at a concentration of at least 1000 mg nimorazole in 100 ml water at 25° C. within 5 minutes upon stirring, thereby providing a dispersion that passes through a sieve screen with a nominal mesh aperture of 710 μm.
3 more elements
(canceled)
Dependencies are inferred from the claim text.