Method and use of nano-scale devices for reduction of tissue injury in ischemic and reperfusion injury
AssigneesThe Board of Trustees of the Leland Stanford Junior University, The Johns Hopkins University
InventorsCorinne Bright, Rachel Bright, Eric Churchill, Kam W. Leong, Daria Mochly-Rosen
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Abstract
A method for protection of tissues subject to ischemic and/or reperfusion damage is provided. The method includes administering to the tissue a composition comprising nanodevices. The nanodevices can take the form of, for example, polymeric nanoparticles or lipidic nanoparticles. The nanodevices also find use in methods for reducing ischemic injury in tissue at risk of such injury, such as heart and brain tissue.
Claims15
A method for reducing ischemic reperfusion injury to a tissue, comprising delivering intravascularly to the tissue a composition comprised of nanodevices.
A method for conferring protection to a tissue at risk of an ischemic reperfusion injury to a tissue, comprising administering intravascularly to the tissue a composition comprised of polymer or lipidic nanodevices.
Dependencies are inferred from the claim text.