Method for increasing etec cs6 antigen presentation on cell surface and products obtainable thereof
AssigneeScandinavian Biopharma Holding AB
InventorsNils Carlin, Ann-Mari Svennerholm, Joshua Tobias
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Abstract
A method for increasing the presentation of ETEC CS6 antigen on cell surface, comprising the step of contacting cells expressing said antigen with an aqueous solution comprising 0.6-2.2 percent phenol by weight, such that the presentation of said antigen is increased by at least 100%. A method for the manufacture of a killed whole cell vaccine for immunization against CS6-expressing ETEC. Cells and vaccines obtainable by the above methods.
Claims28
A method for increasing the presentation of ETEC CS6 antigen on a cell surface, comprising the step of contacting cells expressing said antigen with an aqueous solution comprising 0.6-2.2 percent phenol by weight, such that the presentation of said antigen is increased by at least 100%.
2-15. (canceled)
Dependencies are inferred from the claim text.