Vaccine comprising inactivated cells of haemophilus parasuis bacteria of serotype 5
OwnerMaarten Hendrik Witvliet, Selma Marianne Hensen +1inventors
InventorsMaarten Hendrik Witvliet, Selma Marianne Hensen, Ruud Philip Antoon Maria Segers
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Abstract
The present invention pertains to the use of Haemophilus parasuis bacteria of serotype 5 expressing an iron-restriction protein visible on a Western-blot when reacted with serum of a convalescent animal which has recovered from an infection by Haemophilus parasuis bacteria of serotype 4, the said protein not being visible on a Western-blot when Haemophilus parasuis bacteria of serotype 5 grown under iron-replete conditions, are reacted under the same conditions, in a vaccine to protect a subject animal against a disorder arising from Haemophilus parasuis serotype 4 bacteria.
Claims2
1-4. (canceled)
A method of protecting a pig against a disorder arising from a Haemophilus parasuis serotype 4 bacteria, said method comprising administering a vaccine that comprises inactivated cells of Haemophilus parasuis bacteria of serotype 5 grown under iron-restriction conditions to the pig;
- which bacteria express an iron-restriction protein visible on a Western-blot when reacted with serum of a convalescent animal which has recovered from an infection by Haemophilus parasuis bacteria of serotype 4, the said protein not being visible on a Western-blot when wild-type Haemophilus parasuis bacteria of serotype 5 are grown under iron-replete conditions are reacted under the same conditions.
Dependencies are inferred from the claim text.