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US 2014/0178418 A1Published application
Breast Cancer Vaccine
AssigneeThe Cleveland Clinic Foundation
InventorVincent K. TUOHY
Life of this patent
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Abstract
Compositions and methods for immunization against human breast cancer are disclosed. A breast cancer vaccine comprises an immunogenic polypeptide comprising human α-lactalbumin.
Claims11
1-19. (canceled)
A method of inducing a human proinflammatory immune response to human α-lactalbumin (SEQ ID NO:
- 1), said method comprising the steps of
- exposing human female antigen presenting cells to an antigen consisting of human α-lactalbumin (SEQ ID NO:
- 1) in the presence of human female T cells, to activate said human female T cells, thereby inducing said proinflammatory human immune response.
A method of inducing a human proinflammatory immune response to human α-lactalbumin (SEQ ID NO:
- 1), said method comprising the steps of
- exposing purified human female antigen presenting cells to human α-lactalbumin (SEQ ID NO:
- 1) in the presence of purified human female T cells, to activate said purified human female T cells, thereby inducing said proinflammatory human immune response.
Dependencies are inferred from the claim text.