Back to results
US 2014/0178394 A1Published application
Novel antigen peptide and uses thereof
AssigneesUniversite D'Aix-Marseille, INSERM (Insititut Nationa de la Sante et de la Rec Recherche Medicals), Institut Jean Paoli & Irene Calmettes
InventorsMarc Lopez, Daniel Olive
Life of this patent
Estimating the term…
Abstract
The invention relates to antigen peptide derived from the Nectin4 and its use for preventing and treating cancer.
Claims17
A antigen peptide comprising an amino acid motif having an amino acid sequence:
- VLVPPLPSL (SEQ ID NO:
- 2),
- wherein the amino acid sequence of the amino acid motif may differ from VLVPPLPSL by 1, 2 or 3 amino acids.
6-9. (canceled)
(canceled)
A method of preventing or treating cancer in a subject in need thereof, comprising
- administering to the subject a therapeutically effective amount of at least one antigen peptide comprising an amino acid motif VLVPPLPSL (SEQ ID NO:
- 2), wherein the amino acid sequence of the amino acid motif may differ from VLVPPLPSL by 1, 2 or 3 amino acids.
A method of preventing or treating cancer in a subject in need thereof, comprising
- administering to the subject a therapeutically effective amount of a composition for adoptive therapy comprising T lymphocytes that recognize specifically an antigen peptide comprising an amino acid motif having an amino acid sequence VLVPPLPSL (SEQ ID NO:
- 2), wherein the amino acid sequence of the amino acid motif may differ from VLVPPLPSL by 1, 2 or 3 amino acids.
Dependencies are inferred from the claim text.