Colon disease targets and uses thereof

An isolated nucleic acid molecule comprising a nucleotide sequence selected from the group consisting of:

• a) SEQ ID NOS:684-1331;
• b) nucleotide sequences that encode a protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-683 and 1332-1501;
• and
• c) nucleotide sequences that are completely complementary to the nucleotide sequences of a) or b).

A method of diagnosing, prognosing, or determining risk of colon cancer in a subject, the method comprising detecting at least one molecule in a sample, wherein the presence or abundance of the molecule is indicative of colon cancer, and wherein the molecule is selected from the group consisting of:

• a) proteins comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-683 and 1332-1501;
• b) antibodies that selectively bind to the protein of a);
• c) nucleic acid molecules comprising a nucleotide sequence selected from the group consisting of SEQ ID NOS:684-1331 and nucleotide sequences that encode the protein of a);
• and
• d) nucleic acid molecules comprising a nucleotide sequence that is completely complementary to the nucleic acid molecule of c).