Combinations of anti-4-1bb antibodies and adcc-inducing antibodies for the treatment of cancer
OwnerLeslie Lynne Sharp, Timothy Scott Fisher +1inventors
InventorsLeslie Lynne Sharp, Timothy Scott Fisher, Mark William Elliott
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Abstract
Methods for treating cancer in a patient in need thereof, with a therapeutically effective amount of an anti-4-1BB antibody in combination with a therapeutically effective amount of an ADCC-inducing antibody, are disclosed.
Claims15
A method for the treatment of cancer in a patient in need of such treatment, said method comprising administering to said patient a therapeutically effective amount of an anti-4-1BB antibody, or antigen-binding portion thereof, in combination with a therapeutically effective amount of an anti-CD20 antibody, or antigen-binding portion thereof.
A method for the treatment of cancer in a patient in need of such treatment, said method comprising administering to said patient a therapeutically effective amount of MOR-7480.1, or antigen-binding portion thereof, in combination with a therapeutically effective amount of rituximab, or antigen-binding portion thereof.
A method for the treatment of cancer in a patient in need of such treatment, said method comprising administering to said patient a therapeutically effective amount of an anti-4-1BB antibody, or antigen-binding portion thereof, in combination with a therapeutically effective amount of an anti-P-cadherin antibody, or antigen-binding portion thereof.
Dependencies are inferred from the claim text.