Methods of Treating Inflammatory Diseases by Targeting the Chemoattractant Cytokine Receptor 2 (CCR2) or Chemokine (C-C motif) Ligand 2 (CCL2)
AssigneeThe Brigham and Women's Hospital, Inc.
InventorsHoward Weiner, Oleg Butovsky
Life of this patent
Estimating the term…
Abstract
Methods of treating inflammatory diseases, e.g., diseases associated with inflammatory CD14+/CD16− monocytes, e.g., amyotrophic lateral sclerosis (ALS), stroke, and glaucoma, using compounds such as small molecules and antibodies that target CCR2 or CCL2.
Claims16
A method of treating a subject suffering from a condition selected from the group consisting of amyotrophic lateral sclerosis (ALS), stroke, and glaucoma, the method comprising administering to the subject an effective amount of a compound that binds to Chemoattractant Cytokine Receptor 2 (CCR2) or Chemokine (C—C motif) Ligand 2 (CCL2).
A method of reducing inflammation in a subject suffering from a condition selected from the group consisting of ALS, stroke, and glaucoma, the method comprising administering to the subject an effective amount of a compound that binds to CCR2 or Chemokine (C—C motif) Ligand 2 (CCL2).
Dependencies are inferred from the claim text.