Loading patent…
AssigneesThe United States of America, as represented by the Secretary, Department of Health and Human Servi, Metanomics Health GmbH
InventorsAlexander Strigun, Lisette Leonhardt, Dörthe Ahlbory-Dieker, Lisa M. Pence, Richard Beger
Estimating the term…
The present invention concerns means and methods for predicting the risk of a subject to suffer from liver damage. In particular, it pertains to a method for predicting the risk of a subject to suffer from liver damage caused by acetaminophen comprising determining the amount of putrescine in a blood, serum or plasma sample that has been obtained from the subject after administration of acetaminophen, and comparing the determined amount to a reference, whereby the risk of the subject to suffer from liver damage caused by acetaminophen is predicted. Also provided are devices for carrying out the aforementioned methods.
A method for predicting the risk of a subject to suffer from liver damage caused by acetaminophen, comprising
A data storage medium comprising a data collection comprising characteristic values for putrescine, and, optionally, for at least one further marker selected from the group consisting of myo-inositol, lysophosphatidylcholine (C18:1) and o-phosphoethanolamine.
A diagnostic composition comprising putrescine, and, optionally, for at least one further marker selected from the group consisting of myo-inositol, lysophosphatidylcholine (C18:1) and o-phosphoethanolamine, or means for the determination thereof.
Dependencies are inferred from the claim text.