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US 2014/0176704 A1Published application
Fluid stream imaging apparatus
AssigneeCytonome/St, LLC
InventorDonald Francis Perrault, JR.
Life of this patent
Estimating the term…
Abstract
A fluid stream imaging apparatus having either optics for manipulating the aspect ratio or sensing elements configured for manipulating the aspect ratio of an image of the fluid stream. This application may also relate to a system for acquiring images of a portion of a fluid stream at high speeds for image processing to measure and predict droplet delays for individual forming particles.
Claims20
A flow cytometer comprising:
- a. a fluid delivery system having a nozzle for producing a fluid stream, the fluid delivery system having an oscillator for perturbing the fluid stream into droplet at a break off point downstream of the nozzle;
- b. an excitation energy source for interrogating the fluid stream at an inspection zone;
- c. an optical system for producing a image of the fluid stream, the image of the fluid stream including at least the inspection zone and the break off point;
- and
- d. a high resolution sensing element for sensing an image of the fluid stream.
2 more elements
A flow cytometer comprising:
- a. a fluid delivery system having a nozzle for producing a fluid stream, the fluid delivery system having an oscillator for perturbing the fluid stream into droplet at a break off point downstream of the nozzle;
- b. an excitation energy source for interrogating the fluid stream at an inspection zone;
- c. a detector for detecting electromagnetic radiation from particles at the inspection zone and for determining particle characteristics;
- d. a controller for charging the fluid stream based on the detected particle characteristics;
- e. an optical system for producing a image of the fluid stream, the image of the fluid stream including at least the break off point, wherein the optical system takes multiple images per droplet;
- f. a sensing element for sensing a plurality of images of the fluid stream;
- and
- g. a processor for processing the detected image of the fluid stream, wherein the processor is responsive to images of the fluid stream to determine the time at which a droplet breaks off the fluid stream.
5 more elements
Dependencies are inferred from the claim text.