Field Effect Transistor-Based Bio Sensor
AssigneeInternational Business Machines Corporation
InventorsAli Afzali-Ardakani, Christopher P. D'Emic, Ashish Jagtiani, Sufi Zafar
Life of this patent
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Abstract
An apparatus comprises: a sensing element formed on a buried oxide layer of a substrate and providing communication between a source region and a drain region; a gate dielectric layer on the sensing element, the gate dielectric layer defining a sensing surface on the sensing element; a passive surface surrounding the sensing surface; and a compound bound to the sensing surface and not bound to the passive surface, the compound having a ligand specifically configured to preferentially bind a target molecule to be sensed. An electrolyte solution in contact with the sensing surface and the passive surface forms a top gate of the apparatus.
Claims12
An apparatus, comprising:
- a sensing element formed on a buried oxide layer of a substrate and providing communication between a source region and a drain region;
- a gate dielectric layer on the sensing element, the gate dielectric layer defining a sensing surface on the sensing element;
- a passive surface surrounding the sensing surface, the passive surface being of a material that is dissimilar to a material of the sensing surface;
- and
- a compound bound to the sensing surface and not bound to the passive surface, the compound having a ligand specifically configured to preferentially bind a target molecule to be sensed;
- wherein an electrolyte solution in contact with the sensing surface and the passive surface forms a top gate of the apparatus.
An SOI finFET-based sensor, comprising:
- a sensing element formed on a substrate having a source region and a drain region, the sensing element comprising a silicon member extending between the source region and the drain region;
- a gate dielectric layer formed over the sensing element, the gate dielectric layer comprising a sensing surface over the sensing element;
- a passive surface surrounding, adjacent to, or around the sensing surface, a material of the passive surface being dissimilar to a material of the sensing surface;
- and
- a hydroxamic acid bound to the sensing surface and not bound to the passive surface, the hydroxamic acid having a ligand specifically configured to preferentially bind a target molecule to be sensed.
12-17. (canceled)
Dependencies are inferred from the claim text.