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US 2014/0174957 A1Published application
Ophthalmic Devices For Delivery Of Beneficial Agents
AssigneeCooperVision International Holding Company, LP
InventorsVictoria Rogers, Andrew Luk, Arthur Back, Samuel Zalipsky
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Abstract
Contact lenses comprising phosphorylcholine groups release beneficial polyionic or guanidinium-containing agents.
Claims23
An unworn contact lens immersed in a packaging solution and sealed in a package, said contact lens comprising:
- (a) a hydrogel comprising integral phosphorylcholine groups;
- and
- (b) a releasable ionic agent electrostatically bound to the phosphorylcholine groups, wherein the ionic agent is polyionic or comprises at least one guanidinium group or is both polyionic and comprises at least one guanidinium group.
A method of manufacturing a contact lens, said method comprising:
- a) polymerizing a monomer mixture comprising 2-methacryloyloxyethyl phosphorylcholine (MPC) to provide an non-hydrated lens-shaped polymerization product;
- b) immersing the non-hydrated lens-shaped polymerization product in a package containing a packaging solution comprising an ionic agent;
- and
- c) sealing the package, wherein the ionic agent electrostatically attaches to phosphorylcholine groups on the MPC.
1 more element
Dependencies are inferred from the claim text.