Electrochemical competition sensor
AssigneeNewSouth Innovations Pty Limited
InventorsJustin Gooding, Guozhen Liu
Life of this patent
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Abstract
A method for detecting the presence of an analyte in a sample. The method comprises the steps of: adding to the sample an antibody of the analyte; exposing to the sample a binding moiety capable of becoming associated with the antibody of the analyte, the binding moiety being associated with a redox active species that is bound to an electrode and electrochemically accessible to the electrode; and taking amperometric electrochemical measurements which indicate whether the electrochemistry of the redox active species has been modulated by the binding moiety associating with the antibody of the analyte.
Claims20
A method for detecting the presence of an analyte in a sample, the method comprising the steps of:
- adding to the sample an antibody of the analyte;
- exposing to the sample a binding moiety capable of associating with the antibody of the analyte, the binding moiety being associated with a redox active species that is bound to an electrode and electrochemically accessible to the electrode;
- and
- taking amperometric electrochemical measurements which indicate whether the electrochemistry of the redox active species has been modulated by the binding moiety associating with the antibody of the analyte.
A method for determining blood glucose levels in a patient, the method comprising the steps of:
- adding to a sample of the patient's blood an antibody of HbA1c;
- exposing to the sample a binding moiety capable of associating with the antibody of Hb1Ac, the binding moiety being associated with a redox active species that is bound to an electrode and electrochemically accessible to the electrode;
- and
- taking amperometric electrochemical measurements which indicate whether the electrochemistry of the redox active species has been modulated by the binding moiety associating with the antibody of HbA1c.
An amperometric electrochemical sensor for detecting an analyte, the sensor comprising:
- an electrode;
- a redox active species that is electrochemically accessible to the electrode;
- and
- a binding moiety capable of associating with an antibody of the analyte;
- whereby association of the binding moiety with the antibody of the analyte affects the electrochemistry of the redox active species.
Dependencies are inferred from the claim text.