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US 2014/0174926 A1Published application
Molecular diagnostics platform
AssigneeAdvanced Liquid Logic, Inc.
InventorsDonovan Bort, Carrie Graham, Vamsee Pamula, Michael Pollack, Ramakrishna Sista, Vijay Srinivasan
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Abstract
A method of mixing a droplet, the method comprising providing a droplet on a surface, forming the droplet into a first “U” shape having a bottom region and two terminal ends, and simultaneously merging the terminal ends and splitting the droplet at the bottom region to form a second “U” shape which is substantially opposite the first “U” shape.
Claims44
A method of mixing a droplet, the method comprising:
- (a) providing a droplet on a surface;
- (b) forming the droplet into a first “U” shape having a bottom region and two terminal ends;
- (c) simultaneously merging the terminal ends and splitting the droplet at the bottom region to form a second “U” shape which is substantially opposite the first “U” shape.
A droplet actuator comprising:
- (a) a first substrate having a flat surface;
- (b) a second substrate separated from the first substrate to form a droplet operations gap;
- (c) an opening in the second substrate forming a fluid path from an external locus of the droplet actuator into the droplet operations gap;
- (d) a dried reagent pellet having a flat surface situated on the first substrate and aligned with the opening, wherein the flat surface of the dried reagent pellet abuts the flat surface of the first substrate.
1 more element
A droplet actuator comprising:
- (a) one or more substrates arranged to form a droplet operations gap;
- (b) an arrangement of electrodes associated with one or both substrates, the electrodes comprising:
- (i) a central path of electrodes;
- (ii) flanking electrodes arranged on either side of the central path of electrodes.
1 more element
A droplet actuator comprising:
- (a) one or more substrates arranged to form a droplet operations gap, the droplet operations gap comprising a region of gap height transition in which the gap height of the droplet operations gap transitions from a first gap height to a second gap height;
- (b) electrodes associated with the one or more substrates arranged for conducting droplet operations, the electrodes comprising a transition electrode which traverses the region of gap height transition.
A droplet actuator comprising:
- (a) a droplet operations surface;
- (b) an arrangement of electrodes associated with the droplet operations surface, the electrodes comprising:
- (i) a dispensing electrode having a first footprint area;
- (ii) a path of electrodes having a second footprint area, which is smaller than the first footprint area, wherein at least one electrode of the path of electrodes is inset into the dispensing electrode;
- and
- (iii) a set of flanking electrodes flanking two or more electrodes of the path of electrodes.
3 more elements
Dependencies are inferred from the claim text.