# US 2014/0155975 A1 · Cardiac rhythm management system with intramural myocardial pacing leads and electrodes

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- Number: US 2014/0155975 A1
- Document ID: US20140155975A1
- Status: Published application
- Kind: A1
- Application number: 13/902,973
- Filed: 2013-05-27
- Published: 2014-06-05
- Earliest claimed: 2002-07-26
- Assignees: Richard C. Satterfield
- Inventors: William P. Santamore; Jeanne M. Lesniak
- Web page: https://patentgrep.com/patent/US20140155975A1

## CPC

- A61N 1/0587: {Epicardial electrode systems; Endocardial electrodes piercing the pericardium}
- A61N 1/056: {Transvascular endocardial electrode systems}
- A61N 1/0568: {with drug delivery}
- A61N 1/057: {Anchoring means; Means for fixing the head inside the heart}
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)

## Abstract

Medical devices and therapeutic methods for use in the field of cardiology, cardiac rhythm management and interventional cardiology, and more specifically to catheter-based systems for implantation of pacing leads and electrodes, or intramural myocardial reinforcement devices, within the myocardial wall of the heart, such as the ventricles, to provide improved cardiac function.

## Claims

### Claim 1

A method for direct localized therapeutic treatment of myocardial tissue in heart having a pathological condition comprising the steps of:
a. identifying a target region of the myocardium having an epicardial region and an endocardial region and an intramural space defined between;
b. delivering a lead having an electrode to said intramural space; wherein said electrode is configured to be connected to a therapeutic or diagnostic device, and wherein the mechanical properties of at least a portion of the myocardial tissue of the target region substantially identified in step (a) is physically modified.

### Claim 2 (depends on 1)

The method of claim 1 wherein the modified mechanical properties include an increase in systolic performance.

### Claim 3 (depends on 1)

The method of claim 1 wherein the therapeutic or diagnostic device is a pacemaker.

### Claim 4 (depends on 1)

The method of claim 1 wherein the therapeutic or diagnostic device is a cardioverter/defibrillator.

### Claim 5 (depends on 1)

The method of claim 1 wherein the therapeutic or diagnostic device is a cardiac resynchronization device.

### Claim 6 (depends on 2)

The method of claim 2 wherein the modified mechanical properties include substantially no decrease in diastolic performance.

### Claim 7 (depends on 1)

The method of claim 1, wherein said target region includes a myocardial infarct or ischemic zone.

### Claim 8 (depends on 7)

The method of claim 7, wherein the lead includes an electro active bridge for spanning said infarct or ischemic zone.

### Claim 9 (depends on 1)

The method of claim 1, wherein said delivering step further comprises delivering a substantially arcuately curved lead into the intramural space.

### Claim 10 (depends on 9)

The method of claim 9 wherein said delivering step further comprises using a stylet.

### Claim 11 (depends on 9)

The method of claim 9 wherein said delivering step further comprises using a guidewire.

### Claim 12 (depends on 1)

The method of claim 1, wherein said lead further comprises echo features for aiding visualization.

### Claim 13 (depends on 1)

The method of claim 1, wherein said lead further comprises radiopaque features.

### Claim 14 (depends on 1)

The method of claim 1, wherein said lead further comprises a drug eluting surface.