# US 2014/0155776 A1 · Methods, apparatus and systems for monitoring co2

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- Number: US 2014/0155776 A1
- Document ID: US20140155776A1
- Status: Published application
- Kind: A1
- Application number: 14/176,077
- Filed: 2014-02-08
- Published: 2014-06-05
- Earliest claimed: 2008-05-28
- Assignees: Oridion Medical 1987 Ltd.
- Applicants: Oridion Medical 1987 Ltd.
- Inventors: Joshua Lewis Colman; Iris Shalev Stein
- Web page: https://patentgrep.com/patent/US20140155776A1

## CPC

- A61B 5/7282: {Event detection, e.g. detecting unique waveforms indicative of a medical condition (cough events A61B5/0823; seizures A61B5/4094; sleep apnoea A61B5/4818)}
- A61B 5/0205: Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
- A61B 5/082: {Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath (A61B5/083, A61B5/091 take precedence)}
- A61B 5/0836: {Measuring rate of CO2 production}
- A61B 5/097: Devices for facilitating collection of breath or for directing breath into or through measuring devices
- A61B 5/7246: {using correlation, e.g. template matching or determination of similarity}
- A61B 5/7264: {Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems}
- A61B 5/742: {using visual displays (displays for heart-related electrical signals, e.g. ECG, A61B5/339)}
- A61B 5/746: {Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms}
- A61B 10/00: Instruments for taking body samples for diagnostic purposes (for taking samples of blood A61B5/15); Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
- A61M 5/1723: {using feedback of body parameters, e.g. blood sugar or pressure}
- A61M 16/0057: {Pumps therefor}
- A61M 16/0069: {the speed thereof being controlled by respiratory parameters, e.g. by inhalation}
- A61M 16/04: Tracheal tubes (catheters in general A61M25/00)
- A61M 16/0463: {combined with suction tubes, catheters or the like; Outside connections}
- A61M 16/0484: {at the distal end}
- A61M 16/0486: {Multi-lumen tracheal tubes}
- A61M 16/0488: {Mouthpieces; Means for guiding, securing or introducing the tubes (guiding or introducing with laryngoscopes A61B1/267; holding devices on the body A61M25/02)}
- A61M 16/0816: {Joints or connectors}
- A61M 16/085: {Gas sampling}
- A61M 16/20: Valves specially adapted to medical respiratory devices
- A61B 5/021: Measuring pressure in heart or blood vessels
- A61B 5/024: Measuring pulse rate or heart rate
- A61B 5/0816: {Measuring devices for examining respiratory frequency (measuring frequency of electric signals G01R23/00)}
- A61B 5/0833: {Measuring rate of oxygen consumption}
- A61B 5/087: Measuring breath flow
- A61B 2010/0087: {Breath samples}
- A61M 16/0096: {High frequency jet ventilation}
- A61M 2016/0413: {with detectors of CO2 in exhaled gases}
- A61M 2016/103: {the CO2 concentration}
- A61M 2230/432: partial CO2 pressure (P-CO2)
- G06N 5/04: Inference or reasoning models
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}
- G06N: COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS

## Abstract

There is provided herein methods, apparatus and systems for evaluating carbon dioxide (CO2) concentration in a subject's breath, for example in subjects ventilated with High Frequency Ventilation (HFV), the method includes inserting to a trachea of a subject an endotrachial tube (ETT), sampling breath from an area in the trachea located in proximity to a distal end of the endotrachial tube (ETT) and evaluating one or more CO2 related parameters of the sampled breath.

## Claims

### Claim 1

A double lumen endotracheal tube (ETT) comprising a main endotracheal tube and a second endotracheal tube, wherein a distal opening of the second endotracheal tube is located inside the main endotracheal tube and proximal to a distal opening thereof.

### Claim 2 (depends on 1)

The double lumen endotracheal tube (ETT) of claim 1, wherein the second endotracheal tube is located essentially inside the lumen of the main endotracheal tube.

### Claim 3 (depends on 2)

The double lumen endotracheal tube (ETT) of claim 2, wherein the second endotracheal tube is located essentially inside an inner wall of the main endotracheal tube.

### Claim 4 (depends on 1)

The double lumen endotracheal tube (ETT) of claim 1, wherein the second endotracheal tube is located outside the main endotracheal tube.

### Claim 5 (depends on 1)

The double lumen endotracheal tube (ETT) of claim 1, wherein the second endotracheal tube has a diameter smaller than the diameter of the main endotracheal tube.

### Claim 6 (depends on 1)

The double lumen endotracheal tube (ETT) of claim 1, for use with children, infants and/or neonates.

### Claim 7 (depends on 1)

The double lumen endotracheal tube (ETT) of claim 1, being an uncuffed endotracheal tube (ETT).

### Claim 8 (depends on 1)

The double lumen endotracheal tube (ETT) of claim 1, configured to sample breath from a distal area of a trachea of a subject.

### Claim 9

A breath sampling system comprising:
a double lumen endotracheal tube (ETT) comprising a main endotracheal tube and a second endotracheal tube, wherein a distal opening of the second endotracheal tube is located inside the main endotracheal tube and proximal to a distal opening thereof; and
an airway adapter.

### Claim 10 (depends on 9)

The system of claim 9, further comprising a first sampling line configured to be connected to said second endotracheal tube and to receive breath samples therefrom; and a second sampling line configured to be connected to said airway adapter and to sample breath therefrom.

### Claim 11 (depends on 10)

The system of claim 10, further comprising a stop-cock configured to switch between sampling from said first sampling line and from said second sampling line.

### Claim 12 (depends on 10)

The system of claim 10, wherein said first sampling line is connected to said second endotracheal tube through a connector.

### Claim 13 (depends on 12)

The system of claim 12, wherein said connector further comprises a suction port adapted to connect to a fluid suction device and/or to facilitate administration of medical agents.