# US 2014/0155716 A1 · Light Wavelength Selection for Avoidance of Surgical Dyes > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2014/0155716 A1 - Document ID: US20140155716A1 - Status: Published application - Kind: A1 - Application number: 13/887,178 - Filed: 2013-05-03 - Published: 2014-06-05 - Earliest claimed: 2012-05-03 - Assignees: ViOptix, Inc. - Inventors: Kate LeeAnn Bechtel; Lester John Lloyd - Web page: https://patentgrep.com/patent/US20140155716A1 ## CPC - A61B 5/14551: {for measuring blood gases} - A61B 5/0059: {using light, e.g. diagnosis by transillumination, diascopy, fluorescence (photoacoustic A61B5/0093; optical measurement of heart rate A61B5/02416; optical measurement of blood flow A61B5/0261; optical measurement of analytes A61B5/1455)} - A61B 5/0075: {by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy (A61B5/0071 takes precedence)} - A61B 5/14546: {for measuring analytes not otherwise provided for, e.g. ions, cytochromes} - A61B 5/1455: using optical sensors, e.g. spectral photometrical oximeters - A61B 5/14552: {Details of sensors specially adapted therefor} - A61B 5/1459: invasive, e.g. introduced into the body by a catheter - A61B 5/1495: Calibrating or testing of in-vivo probes - A61B 5/72: {Signal processing specially adapted for physiological signals or for diagnostic purposes} - A61B 5/7246: {using correlation, e.g. template matching or determination of similarity} - A61B 5/7282: {Event detection, e.g. detecting unique waveforms indicative of a medical condition (cough events A61B5/0823; seizures A61B5/4094; sleep apnoea A61B5/4818)} - A61B 5/74: {Details of notification to user or communication with user or patient; User input means} - A61B 5/7405: {using sound} - A61B 5/742: {using visual displays (displays for heart-related electrical signals, e.g. ECG, A61B5/339)} - A61B 5/7475: {User input or interface means, e.g. keyboard, pointing device, joystick} - A61B 90/11: with guides for needles or instruments, e.g. arcuate slides or ball joints - A61B 90/39: {Markers, e.g. radio-opaque or breast lesions markers} - A61M 35/003: {Portable hand-held applicators having means for dispensing or spreading integral media (hand-held massage devices with liquid delivery A61H7/003)} - A61B 2090/065: {for measuring contact or contact pressure} - A61B 2090/306: {using optical fibres} - A61B 2090/395: {with marking agent for marking skin or other tissue} - A61B 2560/0431: Portable apparatus, e.g. comprising a handle or case - A61B 2560/0475: Special features of memory means, e.g. removable memory cards - A61B 2562/0271: Thermal or temperature sensors - A61B 2562/166: the sensor is mounted on a specially adapted printed circuit board - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} ## Abstract A tissue oximetry device utilizes at least three or at least four different wavelengths of light for collection of reflectance data where the different wavelengths are longer than 730 nanometers. The three or four wavelengths are utilized to generate a range of reflectance data suited for accurate determination of oxygenated hemoglobin and deoxygenated hemoglobin concentrations. The relatively long wavelengths decrease optical interference from certain dyes, particularly methylene blue and PVPI, which may be present on tissue being analyzed for viability and further enhance the generation of accurate reflectance data. The wavelengths are 760 nanometers, 810 nanometers, and 850 nanometers, or 760 nanometers, 810 nanometers, 850 nanometers, and 900 nanometers. ## Claims ### Claim 1 A tissue oximetry device comprising: a processor; a memory coupled to the processor; a plurality of light sources configured to be controlled by the processor, wherein the light sources are configured to generate and emit at least two wavelengths of light longer than 730 nanometers; and a plurality of detectors configured to be controlled by the processor, wherein the processor is configured to: control the plurality of light sources to generate and emit the light into tissue, control the plurality of detectors to detect the light subsequent to reflection of the light from the tissue, control the plurality of detectors to generate reflectance data for the tissue based on detection of the light by the plurality of detectors, and determine the oxygen saturation for the tissue based on the reflectance data. ### Claim 2 (depends on 1) The tissue oximetry device of claim 1 wherein the at least two wavelengths are approximately 760 nanometers and 850 nanometers. ### Claim 3 (depends on 1) The tissue oximetry device of claim 1 wherein the processor is configured to determine concentrations of oxygenated hemoglobin and deoxygenated hemoglobin in the tissue by solving a set of reflectance coefficient equations from the reflectance data for the at least two wavelengths. ### Claim 4 (depends on 1) The tissue oximetry device of claim 1 wherein the plurality of light sources is configured to generate and emit at least three wavelengths of light longer than 730 nanometers. ### Claim 5 (depends on 4) The tissue oximetry device of claim 4 wherein the at least three wavelengths are approximately 760 nanometers, 810 nanometers, and 850 nanometers. ### Claim 6 (depends on 1) The tissue oximetry device of claim 1 wherein the plurality of light sources is configured to generate and emit at least four wavelengths of light longer than 730 nanometers. ### Claim 7 (depends on 6) The tissue oximetry device of claim 6 wherein the at least four wavelengths are approximately 760 nanometers, 810 nanometers, 850 nanometers, and 900 nanometers. ### Claim 8 (depends on 1) The tissue oximetry device of claim 1 wherein the at least two wavelengths are on either side of the isosbestic point. ### Claim 9 (depends on 1) The tissue oximetry device of claim 1 wherein one of the at least two wavelengths is approximately at the isosbestic point. ### Claim 10 A tissue oximetry device comprising: a processor; a memory coupled to the processor; a plurality of light sources configured to be controlled by the processor, wherein the light sources are configured to generate and emit at least two wavelengths of light that are longer than wavelengths of primary absorption peaks of methylene blue; and a plurality of detectors configured to be controlled by the processor, wherein the processor is configured to: control the plurality of light sources to generate and emit the light into tissue; control the plurality of detectors to detect the light subsequent to reflection of the light from the tissue; control the plurality of detectors to generate reflectance data for the tissue based on detection of the light by the plurality of detectors; and determine the oxygen saturation for the tissue based on the reflectance data. ### Claim 11 (depends on 10) The tissue oximetry device of claim 10 wherein the at least two wavelengths of light are longer than wavelengths of primary absorption peaks of povidone-iodine. ### Claim 12 (depends on 10) The tissue oximetry device of claim 10 wherein the at least two wavelengths are approximately 760 nanometers and 850 nanometers. ### Claim 13 (depends on 10) The tissue oximetry device of claim 10 wherein the processor is configured to determine concentrations of oxygenated hemoglobin and deoxygenated hemoglobin in the tissue by solving a set of reflection coefficient equations from the reflectance data for the at least two wavelengths. ### Claim 14 (depends on 10) The tissue oximetry device of claim 10 wherein the plurality of light sources is configured to generate and emit at least three wavelengths of light longer than 730 nanometers. ### Claim 15 (depends on 14) The tissue oximetry device of claim 14 wherein the at least three wavelengths are approximately 760 nanometers, 810 nanometers, and 850 nanometers. ### Claim 16 (depends on 10) The tissue oximetry device of claim 10 wherein the plurality of light sources is configured to generate and emit at least four wavelengths of light longer than 730 nanometers. ### Claim 17 (depends on 16) The tissue oximetry device of claim 16 wherein the at least four wavelengths are approximately 760 nanometers, 810 nanometers, 850 nanometers, and 900 nanometers. ### Claim 18 (depends on 10) The tissue oximetry device of claim 10 wherein the at least two wavelengths are on either side of the isosbestic point. ### Claim 19 (depends on 10) The tissue oximetry device of claim 10 wherein one of the at least two wavelengths is approximately at the isosbestic point.