# US 2014/0155714 A1 · Apparatus and Method for Beneficial Modification of Biorhythmic Activity

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- Number: US 2014/0155714 A1
- Document ID: US20140155714A1
- Status: Published application
- Kind: A1
- Application number: 14/174,437
- Filed: 2014-02-06
- Published: 2014-06-05
- Earliest claimed: 2002-12-13
- Assignees: Intercure Ltd.
- Applicants: Intercure Ltd.
- Inventors: Benjamin Gavish
- Web page: https://patentgrep.com/patent/US20140155714A1

## CPC

- A61B 5/486: {Biofeedback (using electroencephalography [EEG] A61B5/375)}
- A61B 5/01: Measuring temperature of body parts {; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue} (clinical contact thermometers G01K13/20)
- A61B 5/02007: {Evaluating blood vessel condition, e.g. elasticity, compliance}
- A61B 5/0205: Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
- A61B 5/021: Measuring pressure in heart or blood vessels
- A61B 5/0295: using plethysmography, i.e. measuring the variations in the volume of a body part as modified by the circulation of blood therethrough, e.g. impedance plethysmography
- A61B 5/1118: {Determining activity level}
- A61B 5/14542: {for measuring blood gases (A61B5/14551 takes precedence)}
- A61B 5/14551: {for measuring blood gases}
- A61B 5/329: Load diagnosis, e.g. cardiac stress tests
- A61B 5/384: Recording apparatus or displays specially adapted therefor
- A61B 5/395: Details of stimulation, e.g. nerve stimulation to elicit EMG response
- A61B 5/4857: {Indicating the phase of biorhythm}
- A61B 5/6831: {Straps, bands or harnesses}
- A61B 5/7405: {using sound}
- A61B 5/743: {Displaying an image simultaneously with additional graphical information, e.g. symbols, charts, function plots}
- A61B 7/003: {Detecting lung or respiration noise}
- A61B 5/02416: {using photoplethysmograph signals, e.g. generated by infrared radiation (A61B5/14552 takes precedence)}
- A61B 5/7239: {using differentiation including higher order derivatives}
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

Apparatus is provided, including a sensor, adapted to generate a sensor signal indicative of biorhythmic activity of a user of the apparatus, the sensor signal having a first characteristic, indicative of a voluntary action of the user, and a second characteristic, indicative of a benefit-related variable of the user. The apparatus also includes a control unit, adapted to receive the sensor signal, and, responsive to the second characteristics generate an output signal which directs the user to modify a parameter of the voluntary action indicated by the first characteristic.

## Claims

### Claim 1

A method for facilitating improving health of a user, comprising:
receiving a sensor signal indicative of biorhythmic activity of the user, the sensor signal having a first characteristic, indicative of a voluntary action of the user, and a second characteristic, indicative of a benefit-related variable of the user; and
generating an output signal responsive to the second characteristic, the output signal directing the user to modify a parameter of the voluntary action indicated by the first characteristic.

### Claim 2 (depends on 1)

The method of claim 1, wherein the first characteristic is selected from the list consisting of: a period of an aspect of the sensor signal, a rate of an aspect of the sensor signal, a rise time of an aspect of the sensor signal, a fall time of an aspect of the sensor signal, a time derivative at a point of an aspect of the sensor signal, a maximum of the time derivative, a minimum of the time derivative, an amplitude of a maximum of an aspect of the sensor signal averaged over two or more biorhythmic cycles of the aspect, and an amplitude of a minimum of an aspect of the sensor signal averaged over two or more cycles of the aspect, and wherein receiving the sensor signal comprises receiving the sensor signal having the first characteristic.

### Claim 3 (depends on 1)

The method of claim 1, wherein the second characteristic includes a variability of an aspect of the biorhythmic activity, the aspect selected from the list consisting of: an envelope of the biorhythmic activity, an amplitude of the biorhythmic activity, a period of the biorhythmic activity, a standard deviation (SD) of the envelope, an SD of the amplitude, and an SD of the period, and wherein generating the output signal comprises generating the output signal responsive to the variability of the aspect.

### Claim 4 (depends on 1)

The method of claim 1, wherein generating the output signal comprises: generating the output signal in the form of a game, and altering parameters of the game so as to induce the user to modify the parameter of the voluntary action.

### Claim 5 (depends on 1)

The method of claim 1, wherein the biorhythmic activity includes muscle activity of the user, and wherein receiving the sensor signal comprises receiving the sensor signal indicative of the muscle activity.

### Claim 6 (depends on 1)

The method of claim 1, wherein the biorhythmic activity includes cardiac activity, and wherein receiving the sensor signal comprises receiving the sensor signal indicative of the cardiac activity.

### Claim 7 (depends on 1)

The method of claim 1, wherein receiving the sensor signal comprises making a measurement selected from the list consisting of: a fast temperature measurement, an electrocardiographic measurement, an electromyographic measurement, an electroencephalographic measurement, a blood gas concentration measurement, a measurement made photoelectrically, a photoplethysmographic measurement, a pulse oximeter measurement, a measurement of a concentration of a gas emitted from a tissue, a measurement of an electrical impedance of at least one organ of the user, a measurement of a microvascular property of the user, and a laser Doppler measurement.

### Claim 8 (depends on 1)

The method of claim 1, wherein the benefit-related variable is an amplitude of respiration of the user, and wherein generating the output signal comprises configuring the output signal to direct the user to modify the parameter of the voluntary action so as to cause the improvement in the amplitude of the respiration.

### Claim 9 (depends on 1)

The method of claim 1, wherein the benefit-related variable is selected from the list consisting of: a frequency of respiration of the user, a blood pressure of the user, a blood oxygenation saturation of the user, an end-tidal CO2 level of the user, a tissue oxygenation level of the user, a pulse-wave velocity of the user, variations in a skin blood volume of the user, a measure of peak air flow of the user, an amplitude of a skin pulse volume of the user, an arterial compliance of the user, and a parameter of an electrocardiogram of the user, and wherein generating the output signal comprises configuring the output signal to direct the user to modify the parameter of the voluntary action so as to cause the improvement in the benefit-related variable.

### Claim 10 (depends on 1)

The method of claim 1, wherein generating the output signal comprises generating an intelligible stimulus, so as to direct the user to modify the parameter of the voluntary action.

### Claim 11 (depends on 10)

The method of claim 10, wherein generating the intelligible stimulus comprises generating at least one stimulus selected from the list consisting of: an image, alpha-numeric text, a sound, a sound pattern, and a dynamic graphical pattern, so as to direct the user to modify the parameter of the voluntary action.

### Claim 12 (depends on 1)

The method of claim 1, wherein the biorhythmic activity includes respiration, and wherein receiving the sensor signal comprises receiving the sensor signal indicative of the respiration.

### Claim 13 (depends on 12)

The method of claim 12, wherein receiving the sensor signal comprises sensing respiration by sensing respiratory air flow of the user.

### Claim 14 (depends on 12)

The method of claim 12, wherein receiving the sensor signal comprises sensing respiration by sensing breath sounds of the user.

### Claim 15 (depends on 12)

The method of claim 12, wherein the voluntary action includes the respiration, and wherein generating the output signal comprises generating the output signal to direct the user to modify a parameter of the respiration.

### Claim 16 (depends on 15)

The method of claim 15, wherein the first characteristic includes at least one breathing parameter selected from: inspiration time and expiration time, and wherein receiving the sensor signal comprises receiving the sensor signal having the first characteristic.

### Claim 17 (depends on 15)

The method of claim 15, wherein the first characteristic includes an end-tidal CO2 level of the user, and wherein receiving the sensor signal comprises receiving the sensor signal having the first characteristic.

### Claim 18 (depends on 15)

The method of claim 15, wherein the parameter of the respiration includes one or more timing parameters of the respiration, and wherein generating the output signal comprises generating the output signal to direct the user to modify the timing parameters of the respiration.

### Claim 19 (depends on 18)

The method of claim 18, wherein the timing parameters include a pattern of inspiration and expiration of the user, and wherein generating the output signal comprises generating the output signal to direct the user to modify the pattern.

### Claim 20 (depends on 19)

The method of claim 19, wherein generating the output signal comprises generating the output signal to direct the user to modify the pattern so as to reduce a ratio of a time period of the inspiration to a time period of the expiration.
