# US 2014/0155704 A1 · Methods And Systems For Respiratory Monitoring With Photoplethysmography

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- Number: US 2014/0155704 A1
- Document ID: US20140155704A1
- Status: Published application
- Kind: A1
- Application number: 13/929,396
- Filed: 2013-06-27
- Published: 2014-06-05
- Earliest claimed: 2002-06-20
- Assignees: University of Florida Research Foundation, Inc.
- Inventors: Richard J. Melker; Brian S. Fuehrlein
- Web page: https://patentgrep.com/patent/US20140155704A1

## CPC

- A61B 5/0295: using plethysmography, i.e. measuring the variations in the volume of a body part as modified by the circulation of blood therethrough, e.g. impedance plethysmography
- A61B 5/0205: Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
- A61B 5/0261: {using optical means, e.g. infrared light}
- A61B 5/036: {by means introduced into body tracts (A61B5/032 and A61B5/035 take precedence)}
- A61B 5/0836: {Measuring rate of CO2 production}
- A61B 5/087: Measuring breath flow
- A61B 5/0873: {using optical means}
- A61B 5/14551: {for measuring blood gases}
- A61B 5/14552: {Details of sensors specially adapted therefor}
- A61B 5/4818: {Sleep apnoea}
- A61B 5/4836: {Diagnosis combined with treatment in closed-loop systems or methods (A61B5/0036 takes precedence)}
- A61B 5/6819: {Nose}
- A61B 5/682: {Mouth, e.g., oral cavity; tongue; Lips; Teeth}
- A61B 5/6826: {Finger}
- A61B 5/6829: {Foot or ankle}
- A61B 5/7278: {Artificial waveform generation or derivation, e.g. synthesizing signals from measured signals}
- A61B 5/7282: {Event detection, e.g. detecting unique waveforms indicative of a medical condition (cough events A61B5/0823; seizures A61B5/4094; sleep apnoea A61B5/4818)}
- A61M 16/0003: {Accessories therefor, e.g. sensors, vibrators, negative pressure}
- A61M 16/0051: {with alarm devices}
- A61M 16/0057: {Pumps therefor}
- A61M 16/021: {operated by electrical means (A61M16/202 – A61M16/205 take precedence)}
- A61M 16/0666: {Nasal cannulas or tubing (devices for improving normal breathing through the nose A61F5/08; nose filters A62B23/06; outside holding devices A61M25/02)}
- A61M 16/0672: {Nasal cannula assemblies for oxygen therapy}
- A61M 16/08: Bellows; Connecting tubes {(having means for taking samples G01N1/22); Water traps; Patient circuits}
- A61M 16/085: {Gas sampling}
- A61M 16/20: Valves specially adapted to medical respiratory devices
- A61B 5/02416: {using photoplethysmograph signals, e.g. generated by infrared radiation (A61B5/14552 takes precedence)}
- A61B 5/02427: {Details of sensor}
- A61B 5/0816: {Measuring devices for examining respiratory frequency (measuring frequency of electric signals G01R23/00)}
- A61B 2560/0276: Determining malfunction
- A61B 2562/247: Hygienic covers, i.e. for covering the sensor or apparatus during use
- A61M 2202/0208: Oxygen
- A61M 2202/03: Gases in liquid phase, e.g. cryogenic liquids
- A61M 2205/3561: local, e.g. within room or hospital
- A61M 2205/3569: sublocal, e.g. between console and disposable
- A61M 2210/0618: Nose
- A61M 2210/0625: Mouth
- A61M 2210/0662: Ears
- A61M 2230/06: Heartbeat rate only
- A61M 2230/205: partial oxygen pressure (P-O2)
- A61M 2230/30: Blood pressure (A61M2230/04 takes precedence)
- A61M 2230/42: Rate
- A61M 2230/432: partial CO2 pressure (P-CO2)
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}

## Abstract

The present invention relates to optimized gas supply utilizing photoplethysmography. Flow rate, pressure or amount of gas is adjusted as a function of blood oxygen saturation data, photoplethysmography signals, or both, obtained from the pulse oximeter probe.

## Claims

### Claim 1

A method of monitoring respiration in an individual, comprising isolating a DC component of a plethysmograph; and monitoring with a computer changes in an envelope of the isolated DC component of the plethysmograph to monitor respiration.

### Claim 2 (depends on 1)

The method of claim 1, further comprising quantifying the changes in the envelope of the isolated DC component to determine respiratory rate.

### Claim 3 (depends on 1)

The method of claim 1, wherein the plethysmograph is obtained from a plethysmography probe secured at a central source site.

### Claim 4 (depends on 3)

The method of claim 3, wherein the central source site is the nasal alar.

### Claim 5 (depends on 1)

The method of claim 1, wherein the plethysmograph is obtained from a spontaneously breathing individual.

### Claim 6 (depends on 1)

The method of claim 1, wherein changes in the envelope of the isolated DC component are used to determine the optimal level of positive end expiratory pressure (PEEP).

### Claim 7 (depends on 6)

The method of claim 6, wherein in the method further comprises adjusting the level of PEEP in response to the changes in the envelope of the plethysmograph.

### Claim 8 (depends on 1)

The method of claim 1, further comprising monitoring respiration with a separate monitoring sensor.

### Claim 9 (depends on 8)

The method of claim 8, wherein the separate monitoring sensor detects nasal air pressure, nasal air flow, or both.

### Claim 10 (depends on 8)

The method of claim 8, wherein the separate monitoring sensor comprises a capnography sensor.

### Claim 11

A system for monitoring respiration in an individual comprising: a computer configured to isolate a DC component from a plethysmograph, and to evaluate changes in an envelope of the isolated DC component to determine a breathing cycle of the individual.

### Claim 12 (depends on 11)

The system of claim 11, wherein the computer is further configured to determine respiration rate from the changes in the envelope of the isolated DC component.

### Claim 13 (depends on 11)

The system of claim 11, further comprising a pulse oximetry probe configured to secure to the nose of the individual.

### Claim 14 (depends on 13)

The system of claim 13, wherein the pulse oximetry probe is configured to secure to the nasal alar of the individual.

### Claim 15 (depends on 11)

The system of claim 11, wherein the system is further configured to increase or decrease a supply of oxygen to the individual in response to the changes in the envelope of the isolated DC component.