# US 2014/0155589 A1 · Inhibitory fiber against virulence factors production and method for producing same > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2014/0155589 A1 - Document ID: US20140155589A1 - Status: Published application - Kind: A1 - Application number: 14/234,554 - Filed: 2012-07-25 - Published: 2014-06-05 - Earliest claimed: 2011-07-26 - Assignees: Kurashiki Boseki Kabushiki Kaisha; Kyoto Prefectural Public University Corporation - Inventors: Kohji Miyazaki; Kunihiro Ohshima; Susumu Katsuen - Web page: https://patentgrep.com/patent/US20140155589A1 ## CPC - C08B 5/00: Preparation of cellulose esters of inorganic acids {, e.g. phosphates (rendering cellulose suitable for esterification C08B1/02)} - A01N 25/10: Macromolecular compounds - A01N 25/34: Shaped forms, e.g. sheets, not provided for in any other sub-group of this main group - C08B 3/20: Esterification with maintenance of the fibrous structure of the cellulose (surface esterification of textiles D06M13/00) - D06M 10/00: Physical treatment of fibres, threads, yarns, fabrics or fibrous goods made from such materials, e.g. by ultrasonic waves, corona discharge, irradiation, electric currents or magnetic fields; Physical treatment combined with treatment with chemical compounds or elements - D06M 10/008: {Treatment with radioactive elements or with neutrons, alpha, beta or gamma rays} - D06M 10/08: Organic compounds - D06M 11/38: Oxides or hydroxides of elements of Groups 1 or 11 of the Periodic Table - D06M 11/70: with oxides of phosphorus; with hypophosphorous, phosphorous or phosphoric acids or their salts - D06M 13/184: Carboxylic acids; Anhydrides, halides or salts thereof - D06M 14/04: of vegetal origin, e.g. cellulose or derivatives thereof - D06M 14/22: of vegetal origin, e.g. cellulose or derivatives thereof - D06M 16/00: Biochemical treatment of fibres, threads, yarns, fabrics, or fibrous goods made from such materials, e.g. enzymatic - D06M 2101/06: cellulosic - C08B: POLYSACCHARIDES; DERIVATIVES THEREOF (polysaccharides containing less than six saccharide radicals attached to each other by glycosidic linkages C07H; fermentation or enzyme-using processes C12P19/00; sugar industry C13; production of cellulose D21) - A01N: PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF (preservation of food or foodstuff A23); BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES (preparations for medical, dental or toiletry purposes which kill or prevent the growth or proliferation of unwanted organisms A61K); PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS - D06M: TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS ## Abstract The inhibitory fiber against virulence factors production of the present invention comprises a fiber and an inhibitor of virulence factors production fixed to the fiber by chemical bonding. The inhibitor of virulence factors production includes at least one compound selected from the group consisting of a phosphate group-containing compound, a carboxylic acid group-containing compound, and a ketone group-containing compound. The production method of the present invention comprises: irradiating the fiber with an electron beam; and bringing into contact with the fiber at least one compound selected from the group consisting of a phosphate group-containing compound, a carboxylic acid group-containing compound, and a ketone group-containing compound to chemically bond the at least one compound to the fiber. Another production method of the present invention comprises: bringing an aqueous solution containing phosphoric acid and urea into contact with the cellulose fiber to chemically bond phosphoric ester to the cellulose fiber. ## Claims ### Claim 1 An inhibitory fiber against virulence factors production comprising a fiber and an inhibitor of virulence factors production fixed to the fiber by chemical bonding, wherein the inhibitor of virulence factors production includes at least one compound selected from the group consisting of a phosphate group-containing compound, a carboxylic acid group-containing compound, and a ketone group-containing compound. ### Claim 2 (depends on 1) The inhibitory fiber against virulence factors production according to claim 1, wherein the ratio of the inhibitor of virulence factors production to the fiber is 0.01 to 3 mmol/g. ### Claim 3 (depends on 1) The inhibitory fiber against virulence factors production according to claim 1, wherein the phosphate group-containing compound is one or more selected from the group consisting of phosphoric ester and phosphate. ### Claim 4 (depends on 1) The inhibitory fiber against virulence factors production according to claim 1, wherein the carboxylic acid group-containing compound is one or more selected from the group consisting of acrylate and iminodiacetate. ### Claim 5 (depends on 1) The inhibitory fiber against virulence factors production according to claim 1, wherein the ketone group-containing compound is one or more selected from the group consisting of ethylene glycol monoacetoacetate monomethacrylate and diacetone acrylamide. ### Claim 6 (depends on 1) The inhibitory fiber against virulence factors production according to claim 1, wherein the fiber includes a cellulose fiber. ### Claim 7 A method for producing an inhibitory fiber against virulence factors production comprising a fiber and an inhibitor of virulence factors production fixed to the fiber by chemical bonding, the method comprising: irradiating the fiber with an electron beam; and bringing into contact with the fiber at least one compound selected from the group consisting of a phosphate group-containing compound, a carboxylic acid group-containing compound, and a ketone group-containing compound to chemically bond the at least one compound to the fiber. ### Claim 8 (depends on 7) The method according to claim 7, further comprising an alkali neutralization step after the chemical bonding step. ### Claim 9 A method for producing an inhibitory fiber against virulence factors production comprising a cellulose fiber and an inhibitor of virulence factors production fixed to the cellulose fiber by chemical bonding, the method comprising: bringing an aqueous solution containing phosphoric acid and urea into contact with the cellulose fiber to chemically bond phosphoric ester to the cellulose fiber. ### Claim 10 A method for inhibiting virulence factors production using an inhibitory fiber against virulence factors production, wherein the inhibitory fiber against virulence factors production comprises a fiber and an inhibitor of virulence factors production fixed to the fiber by chemical bonding, and the inhibitor of virulence factors production includes at least one compound selected from the group consisting of a phosphate group-containing compound, a carboxylic acid group-containing compound, and a ketone group-containing compound. ### Claim 11 (depends on 10) The method according to claim 10, wherein the ratio of the inhibitor of virulence factors production to the fiber is 0.01 to 3 mmol/g. ### Claim 12 (depends on 10) The method according to claim 10, wherein the phosphate group-containing compound is one or more selected from the group consisting of phosphoric ester and phosphate. ### Claim 13 (depends on 10) The method according to claim 10, wherein the carboxylic acid group-containing compound is one or more selected from the group consisting of acrylate and iminodiacetate. ### Claim 14 (depends on 10) The method according to claim 10, wherein the ketone group-containing compound is one or more selected from the group consisting of ethylene glycol monoacetoacetate monomethacrylate and diacetone acrylamide. ### Claim 15 (depends on 10) The method according to claim 10, wherein the fiber includes a cellulose fiber. ### Claim 16 A fabric comprising an inhibitory fiber against virulence factors production, wherein the inhibitory fiber against virulence factors production comprises a fiber and an inhibitor of virulence factors production fixed to the fiber by chemical bonding, and the inhibitor of virulence factors production includes at least one compound selected from the group consisting of a phosphate group-containing compound, a carboxylic acid group-containing compound, and a ketone group-containing compound. ### Claim 17 (depends on 16) The fabric according to claim 16, wherein the ratio of the inhibitor of virulence factors production to the fiber is 0.01 to 3 mmol/g. ### Claim 18 (depends on 16) The fabric according to claim 16, wherein the phosphate group-containing compound is one or more selected from the group consisting of phosphoric ester and phosphate. ### Claim 19 (depends on 16) The fabric according to claim 16, wherein the carboxylic acid group-containing compound is one or more selected from the group consisting of acrylate and iminodiacetate. ### Claim 20 (depends on 16) The fabric according to claim 16, wherein the ketone group-containing compound is one or more selected from the group consisting of ethylene glycol monoacetoacetate monomethacrylate and diacetone acrylamide.