# US 2014/0154342 A1 · Sandalwood oil and its uses related to skin disorders > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2014/0154342 A1 - Document ID: US20140154342A1 - Status: Published application - Kind: A1 - Application number: 14/235,387 - Filed: 2012-07-27 - Published: 2014-06-05 - Earliest claimed: 2011-07-28 - Assignees: Santalis Pharmaceuticals, Inc. - Inventors: Ian Clements; Paul Castella; Corey Levenson - Web page: https://patentgrep.com/patent/US20140154342A1 ## CPC - A61K 36/185: Magnoliopsida (dicotyledons) - A61K 8/0212: {Face masks} - A61K 8/922: {of vegetable origin} - A61K 9/0014: {Skin, i.e. galenical aspects of topical compositions (non-active ingredients are additionally classified in A61K47/00; A61K9/0009, A61K9/0021, A61K9/7015, A61K9/7023 take precedence; cosmetic preparations A61K8/00, A61Q; preparations for wound dressings or bandages A61L26/00)} - A61K 31/19: Carboxylic acids, e.g. valproic acid (salicylic acid A61K31/60) - A61K 31/194: having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid - A61K 31/60: Salicylic acid; Derivatives thereof - A61K 33/04: Sulfur, selenium or tellurium; Compounds thereof - A61K 45/06: Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca - A61K 47/10: Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers - A61K 47/26: Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin - A61P 17/00: Drugs for dermatological disorders - A61P 17/06: Antipsoriatics - A61P 17/10: Anti-acne agents - A61P 31/10: Antimycotics - A61Q 9/02: Shaving preparations - A61Q 19/00: Preparations for care of the skin - A61Q 19/10: Washing or bathing preparations - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) - A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS - A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS ## Abstract Provided herein are compositions of sandalwood heartwood oil and methods of making and using such compositions. ## Claims ### Claim 1 A composition comprising: (a) a therapeutically effective amount of sandalwood heartwood oil; (b) sandalwood nut oil. ### Claim 2 (depends on 1) The composition of claim 1, further comprising an active agent selected from the group consisting of acetic acid, acetone, alcloxa, alcohol, alkyl isoquinolinium bromide, allantoin, allyl isothiocyanate, aloe vera, alum, aluminum chlorohydrex, aluminum hydroxide, aluminum sulfate, amiloxate, ammonia solution, ammoniated mercury, amyltricresois, an antibiotic, ascorbic acid, aspirin, bacitracin, basic fuchsin, beeswax, benzalkonium chloride, benzethonium chloride, benzocaine, benzoic acid, benzoxiquine, benzoyl peroxide, benzyl alcohol, bismuth subsalicylate, boric acid, calcium polysulfide, calcium thiosulfate, calcium undecylate, calcium undecylenate, calomel, camphor, camphorated metacresol, candicin, captan, chloral hydrate, chlorhydroxyquinoline (cloxyquin), chlorobutanol, chlorothymol, chloroxylenol, clioquinol, cloflucarban, clotrimazole, coal tar, colloidal oatmeal, copper undecylate, cresol, cyclomethycaine sulfate, dibenzothiophene, dichlorophen,erythromycin, estrone, ethohexadiol, eucalyptol, eugenol, fluorosalan, glycerin, haloprogin, hexachlorophene, hexylresorcinol, hydrocortisone preparations, hydrogen peroxide, iodine-containing ingredient, juniper tar, kaolin, lanolin, lauryl isoquinolinium bromide, mandelic acid, magnesium aluminum silicate, magnesium sulfate, m-cresol, methylparaben, menthol, merbromin, mercufenol chloride, mercuric chloride, mercuric oxide, mercuric salicylate, mercuric sulfide (red), mercury, mercury oleate, mercury sulfide, mercury-containing ingredient, methapyrilene hydrochloride, methyl salicylate, methylbenzethonium chloride, miconazole nitrate, mineral oil, neomycin, nitromersol, nonylphenoxypoly ethanol iodine, nystatin, oxyquinoline, oxyquinoline, oxyquinoline sulfate, PABA, para-chloromercuriphenol, peppermint oil, phenol, phenolate sodium, phenyl salicylate, phenylmercuric nitrate, pine tar, poloxamer 188, poloxamer-iodine complex, potassium, povidone-iodine, propionic acid, propylparaben, pyrilamine maleate, pyrithione zinc, resorcinol, resorcinol monoacetate, salicylamide, salicylic acid, selenium sulfide, shark liver oil, sodium borate, sodium caprylate, sodium propionate, sodium salicylate, sodium thiosulfate, sulfur, tannic acid, tetracaine, tetracaine hydrochloride, tetracycline, thimerosal, thymol, tolindate, tolnaftate, triacetin, triclocarban, triclosan, triple dye, undecoylium chlorideiodine complex, undecylenic acid, vitamin A, vitamin E, vitromersal, zinc acetate, zinc caprylate, zinc oxide, zinc propionate, zinc stearate, zinc sulfide, zinc undecylate, zyloxin and 2-ethylhexyl-4-phenylbenzopohenone-2-carboxylic acid. ### Claim 3 (canceled) ### Claim 4 (canceled) ### Claim 5 (depends on 1) The composition of claim 1, wherein the concentration of the sandalwood heartwood oil is greater than about 0.3% (w/w) to about 10% (w/w). ### Claim 6 (depends on 1) The composition of claim 1, wherein the concentration of the sandalwood nut oil is from about 0.5% to about 10% (w/w). ### Claim 7 (depends on 2) The composition of claim 2, wherein the concentration of the active ingredient is from about 0.25% to about 25% (w/w). ### Claim 8 (depends on 1) The composition of claim 1, further comprising a fruit acid. ### Claim 9 (canceled) ### Claim 10 (depends on 1) The composition of claim 1, further comprising a fruit extract. ### Claim 11 (canceled) ### Claim 12 (depends on 1) The composition of claim 1, further comprising a flower extract. ### Claim 13 (canceled) ### Claim 14 (depends on 1) The composition of claim 1, further comprising a solvent. ### Claim 15 (canceled) ### Claim 16 (depends on 14) The composition of claim 14, wherein the solvent is water or alcohol. ### Claim 17 (canceled) ### Claim 18 (canceled) ### Claim 19 (canceled) ### Claim 20 (canceled) ### Claim 21 (canceled) ### Claim 22 (canceled) ### Claim 23 (depends on 1) The composition of claim 1, wherein the composition is in a form selected from the group consisting of an ointment, lotion, cream, moisturizer, gel, mousse, clay mask, serum, cleanser, shaving cream, shaving gel, soap, shampoo and a stick. ### Claim 24 (canceled) ### Claim 25 (canceled) ### Claim 26 (depends on 1) A method of treating a skin disorder in a subject comprising administering the composition of claim 1 to the subject, where the subject has a skin disorder or is at risk of developing a skin disorder. ### Claim 27 (depends on 26) The method of claim 26, wherein the skin disorder is selected from the group consisting of acne, rosacea, psoriasis, eczema, dermatitis, dandruff, diaper rash and fungal infection. ### Claim 28 (canceled) ### Claim 29 (canceled) ### Claim 30 (canceled) ### Claim 31 An anti-acne composition comprising: (a) an active anti-acne agent; (b) a fruit acid; (c) sandalwood heartwood oil; (d) a fruit extract; and (e) a flower extract. ### Claim 32 (depends on 31) The composition of claim 31, wherein the active anti-acne agent is selected from the group consisting of salicylic acid, benzoyl peroxide, glycolic acid and sulfur. ### Claim 33 (canceled) ### Claim 34 (canceled) ### Claim 35 (depends on 31) The composition of claim 31, wherein the concentration of the heartwood oil is from about 0.25% to about 10% (w/w). ### Claim 36 (canceled) ### Claim 37 (canceled) ### Claim 38 (depends on 31) The composition of claim 31, further comprising a solvent. ### Claim 39 (canceled) ### Claim 40 (canceled) ### Claim 41 (canceled) ### Claim 42 (canceled) ### Claim 43 (canceled) ### Claim 44 (canceled) ### Claim 45 (canceled) ### Claim 46 (canceled) ### Claim 47 (canceled) ### Claim 48 An anti-acne composition comprising: (a) an active anti-acne agent; (b) sandalwood heartwood oil; (c) flower extract; and (d) lemon myrtle leaf extract. ### Claim 49 (depends on 48) The composition of claim 48, wherein the anti-acne agent is selected from the group consisting of salicylic acid, benzoyl peroxide, glycolic acid and sulfur. ### Claim 50 (canceled) ### Claim 51 (canceled) ### Claim 52 (canceled) ### Claim 53 (canceled) ### Claim 54 (depends on 48) The composition of claim 48, further comprising a solvent. ### Claim 55 (canceled) ### Claim 56 (canceled) ### Claim 57 (canceled) ### Claim 58 (depends on 31) The composition of claim 31, wherein the composition is in a form selected from the group consisting of an ointment, lotion, cream, moisturizer, gel, mousse, clay mask, serum, cleanser, shaving cream, shaving gel, shampoo, soap and a stick. ### Claim 59 (canceled) ### Claim 60 (depends on 31) A method of treating acne in a subject comprising administering the composition of claim 31 to the subject, wherein the subject has acne or is at risk of developing acne. ### Claim 61 (canceled) ### Claim 62 (canceled)