# US 2014/0154296 A1 · Dental compositions containing silica microbeads

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- Number: US 2014/0154296 A1
- Document ID: US20140154296A1
- Status: Published application
- Kind: A1
- Application number: 14/176,584
- Filed: 2014-02-10
- Published: 2014-06-05
- Earliest claimed: 2011-04-04
- Inventors: Robert L. Karlinsey
- Web page: https://patentgrep.com/patent/US20140154296A1

## CPC

- A61K 8/25: Silicon; Compounds thereof
- A61K 6/17: Particle size
- A61K 6/816: comprising titanium oxide
- A61K 8/0283: {Matrix particles}
- A61K 8/29: Titanium; Compounds thereof
- A61Q 11/00: Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS

## Abstract

A method for decreasing dental hypersensitivity, including sizing a plurality of non-functionalized microbeads to be between 0.01 μm to 3 μm in diameter, suspending the plurality of non-functionalized microbeads in a fluid matrix to define a dental delivery compositon, introducing the dental delivery composition into an oral cavity, introducing respective non-functionalized microbeads into a dental tubule, adhering respective functionalized microbeads each other and to the dental tubule to define an aggregate, and occluding the dental tubule with the aggregate.

## Claims

### Claim 1

A dental system, comprising:
a dental prophy powder; and
a plurality of generally spherical metal oxide microspheres generally homogeneously dispersed in the dental prophy powder;
wherein each respective microsphere is between about 0.01 micron and about 10 microns in diameter.

### Claim 2 (depends on 1)

The dental system of claim 1 wherein the microspheres are selected from the group comprising titania, alumina, silica, and combinations thereof.

### Claim 3 (depends on 1)

The dental system of claim 1 and further comprising an organic functionalized coating at least partially covering each respective microsphere.

### Claim 4 (depends on 3)

The dental system of claim 3 wherein the organic functionalized coating is an adhesive.

### Claim 5 (depends on 4)

The dental system of claim 4 wherein the organic functionalized coating is hydrophilic.

### Claim 6

A dental polishing system, comprising:
a prophy composition portion; and
a silica microsphere portion homogenouely mixed with the prophy compositon portion to define an admixture;
wherein each respective silica microsphere is between about 0.9 micron and about 3 microns in diameter.

### Claim 7 (depends on 6)

The dental polishing system of claim 6 wherein the prophy composition portion is selected from prophy powders and prophy pastes.

### Claim 8 (depends on 6)

The dental polishing system of claim 6 and further comprising an organic coating at least partially covering the respective silica microspheres.

### Claim 9 (depends on 8)

The dental polishing system of claim 8 wherein the organic coating is selected from the group comprising adhesives, acids, hydrophyllics, colorants, and combinations thereof.

### Claim 10 (depends on 6)

The dental polishing system of claim 6 wherein the admixture further comprises a fluoride portion.

### Claim 11 (depends on 6)

The dental polishing system of claim 6 wherein the admixture further comprises microspheres selected from the group comprising alumina, titania, bioglass, and combinations thereof.

### Claim 12

A dental hypersensitivity and whitening system, comprising:
a plurality of generally spherical inorganic microbeads; and
a prophy polish delivery medium;
wherein the plurality of generally spherical inorganic microbeads are homogeneously suspended in the prophy polish delivery medium to define a prophy delivery composition.

### Claim 13 (depends on 12)

The dental hypersensitivity and whitening system of claim 12, wherein the generally spherical inorganic microbeads are generally composed of an inorganic material from the group comprising silica, titania, alumina, and combinations thereof.

### Claim 14 (depends on 12)

The dental hypersensitivity and whitening system of claim 12, wherein each respective generally spherical inorganic microbead is between 0.01 μm to 3 μm in diameter.

### Claim 15 (depends on 12)

The dental hypersensitivity and whitening system of claim 12, wherein the prophy polish delivery medium is selected from the group of abrasives comprising prophy powders, prophy pastes, and combinations thereof.

### Claim 16 (depends on 12)

The dental hypersensitivity and whitening system of claim 12, wherein the dental delivery system includes fluoride.

### Claim 17 (depends on 12)

The dental hypersensitivity and whitening system of claim 12, wherein the delivery medium adheres to at least two generally spherical inorganic microbeads and to dentin surfaces to define a composite aggregate, and wherein the composite aggregate provides dental remineralization and a sacrificial layer for acid resistance.

### Claim 18 (depends on 12)

The dental hypersensitivity and whitening system of claim 12, wherein the respective generally spherical inorganic microbeads are functionalized with and organic coating.

### Claim 19 (depends on 18)

The dental hypersensitivity and whitening system of claim 18 wherein the organic coating is an adhesive.