# US 2014/0151576 A1 · Optical imaging system

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- Number: US 2014/0151576 A1
- Document ID: US20140151576A1
- Status: Published application
- Kind: A1
- Application number: 14/122,832
- Filed: 2011-06-01
- Published: 2014-06-05
- Earliest claimed: 2011-06-01
- Assignees: Scanco Holding AG
- Applicants: Scanco Holding AG
- Inventors: Kai Hassler; Martina Bucher
- Web page: https://patentgrep.com/patent/US20140151576A1

## CPC

- G01N 21/64: Fluorescence; Phosphorescence
- G01N 21/4795: {spatially resolved investigating of object in scattering medium (in vivo A61B)}
- G01N 21/6456: {Spatial resolved fluorescence measurements; Imaging}
- G01N 2201/0644: Simple baffled tube construction
- G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q)

## Abstract

The invention relates to an optical imaging system (20) comprising an illumination unit (23), a detection unit (24) and a measurement chamber (21) for receiving a subject to be examined, wherein the illumination unit (23) is arranged such in relation to the measurement chamber (21) that it can illuminate a subject placed inside the measurement chamber (21), and wherein the measurement chamber (21) is provided with several fins (31, 31′) for preventing stray light from reaching the detection unit (24), the several fins (31, 31′) being arranged in such a way that at least some of the fins (31, 31′) are in the field of view of the detection unit (24) with the fins (31, 31′) being orientated such that the surfaces (31.1, 31.1′) of the fins that are subjected to illumination by stray light are not visible to the detection unit (24).

## Claims

### Claim 1

Optical imaging system comprising an illumination unit (23), a detection unit (24) and a measurement chamber (21) for receiving a subject to be examined, wherein the illumination unit (23) is arranged such in relation to the measurement chamber (21) that it can illuminate a subject placed inside the measurement chamber (21), characterized in that the measurement chamber (21) is provided with several fins (31, 31′) for preventing stray light from reaching the detection unit (24), the several fins (31, 31′) being arranged in such a way that at least some of the fins (31, 31′) are in the field of view of the detection unit (24) with the fins (31, 31′) being orientated such that the surfaces (31.1, 31.1′) of the fins (31, 31′) that are subjected to illumination by stray light are not visible to the detection unit (24).

### Claim 2 (depends on 1)

Optical imaging system according to claim 1, wherein the several fins (31, 31′) are arranged at an inner wall of the measurement chamber (21).

### Claim 3 (depends on 2)

Optical imaging system according to claim 2, wherein each outermost fin (31′) is mounted at the inner wall of the measurement chamber (21) at the intersection of an outermost ray (33) with the inner wall of the measurement chamber (21), wherein each outermost ray (33) is defined as ray passing through an edge (43) of an entry (40) of the detection unit (24) and through an edge (44) of a projection of a light receiving region of a sensor (45) of the detection unit (24) onto the subject plane (34) inside the measurement chamber (21), with the edge (43) of the entry (40) of the detection unit (24) being on the opposite side of an optical axis (35) of the optical imaging system (20) from the edge (44) of the projection of the light receiving region.

### Claim 4 (depends on 3)

Optical imaging system according to claim 3, wherein the entry (40) of the detection unit (24) is formed as entrance pupil.

### Claim 5 (depends on 3)

Optical imaging system according to claim 3, wherein the inclination of each outermost fin (31′) corresponds to or is steeper than the inclination of a ray (37) running from the intersection of the respective outermost ray (33) with the inner wall of the measurement chamber (21) to the point of intersection (36) of a light beam of the illumination unit (23) with a surface of the subject to be examined.

### Claim 6 (depends on 3)

Optical imaging system according to claim 3, wherein as point of intersection (36) of the light beam with the surface of the subject a virtual point of intersection is chosen corresponding to the point of intersection (36) that is as far away as possible from the inner wall of the measurement chamber (21) where the illumination unit (23) is arranged.

### Claim 7 (depends on 6)

Optical imaging system according to claim 6, wherein the virtual point of intersection (36) is situated further away from the illumination unit (23) as any real point of intersection of the light beam with the surface of a subject to be examined.

### Claim 8 (depends on 6)

Optical imaging system according to claim 6, wherein the distance between the rotation axis (30) of the measurement chamber (21) and the point of intersection (36) is between 0 mm and 20 mm, in particular 5 mm.

### Claim 9 (depends on 3)

Optical imaging system according to claim 3, wherein fins (31) are arranged between each outermost fins (31′) and the optical axis (35) at the inner wall of the measurement chamber (21), each fin (31) being mounted at the intersection of a respective ray (38) passing through an edge (43) of the entry (40) of the detection unit (24) and through the inwardly projecting end of an adjacent, more outwardly mounted fin (31, 31′) on the opposite side of the optical axis (35).

### Claim 10 (depends on 9)

Optical imaging system according to claim 9, wherein the inclination of each fin (31) that is arranged between an outermost fin (31′) and the optical axis (35) corresponds to or is steeper than the inclination of a ray (39) running from the intersection of the respective ray (38) that runs through the edge (43) of the entry (40) of the detection unit (24) and through the inwardly projecting end of the adjacent, more outwardly mounted fin (31, 31′) with the inner wall of the measurement chamber (21) to the point of intersection (36) of the light beam of the illumination unit (23) with the surface of the subject to be examined.

### Claim 11 (depends on 1)

Optical imaging system according to claim 1, wherein the measurement chamber (21) has the shape of a hollow tube (29).

### Claim 12 (depends on 1)

Optical imaging system according to claim 1, wherein the detection unit (24) is arranged on that side of the measurement chamber (21) that is opposite to the side of the measurement chamber (21) where the illumination unit (23) is arranged.

### Claim 13 (depends on 1)

Optical imaging system according to claim 1, wherein the fins (31, 31′) extend in the longitudinal direction of the measurement chamber (21).

### Claim 14 (depends on 1)

Optical imaging system according to claim 1, wherein the fins (31, 31′) are ring-like.

### Claim 15 (depends on 13)

Optical imaging system according to claim 13, wherein the fins (31, 31′) are held by one or more support rings (41).

### Claim 16 (depends on 4)

Optical imaging system according to claim 4, wherein the inclination of each outermost fin (31′) corresponds to or is steeper than the inclination of a ray (37) running from the intersection of the respective outermost ray (33) with the inner wall of the measurement chamber (21) to the point of intersection (36) of a light beam of the illumination unit (23) with a surface of the subject to be examined.

### Claim 17 (depends on 4)

Optical imaging system according to claim 4, wherein as point of intersection (36) of the light beam with the surface of the subject a virtual point of intersection is chosen corresponding to the point of intersection (36) that is as far away as possible from the inner wall of the measurement chamber (21) where the illumination unit (23) is arranged.

### Claim 18 (depends on 17)

Optical imaging system according to claim 17, wherein the virtual point of intersection (36) is situated further away from the illumination unit (23) as any real point of intersection of the light beam with the surface of a subject to be examined.

### Claim 19 (depends on 4)

Optical imaging system according to claim 4, wherein fins (31) are arranged between each outermost fins (31′) and the optical axis (35) at the inner wall of the measurement chamber (21), each fin (31) being mounted at the intersection of a respective ray (38) passing through an edge (43) of the entry (40) of the detection unit (24) and through the inwardly projecting end of an adjacent, more outwardly mounted fin (31, 31′) on the opposite side of the optical axis (35).

### Claim 20 (depends on 19)

Optical imaging system according to claim 19, wherein the inclination of each fin (31) that is arranged between an outermost fin (31′) and the optical axis (35) corresponds to or is steeper than the inclination of a ray (39) running from the intersection of the respective ray (38) that runs through the edge (43) of the entry (40) of the detection unit (24) and through the inwardly projecting end of the adjacent, more outwardly mounted fin (31, 31′) with the inner wall of the measurement chamber (21) to the point of intersection (36) of the light beam of the illumination unit (23) with the surface of the subject to be examined.
