# US 2014/0150792 A1 · System for providing flow-targeted ventilation synchronized to a patient's breathing cycle

> Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt

- Number: US 2014/0150792 A1
- Document ID: US20140150792A1
- Status: Published application
- Kind: A1
- Application number: 14/172,696
- Filed: 2014-02-04
- Published: 2014-06-05
- Earliest claimed: 2007-01-26
- Assignees: CS Medical, Inc.
- Applicants: CS Medical, Inc.
- Inventors: Kent L. Christopher; Stephanie S. Diehl
- Web page: https://patentgrep.com/patent/US20140150792A1

## CPC

- A61M 16/0051: {with alarm devices}
- A61B 5/0836: {Measuring rate of CO2 production}
- A61B 5/0878: {using temperature sensing means}
- A61B 5/097: Devices for facilitating collection of breath or for directing breath into or through measuring devices
- A61B 5/4836: {Diagnosis combined with treatment in closed-loop systems or methods (A61B5/0036 takes precedence)}
- A61B 5/6852: {Catheters}
- A61M 16/0066: {Blowers or centrifugal pumps}
- A61M 16/024: {including calculation means, e.g. using a processor}
- A61M 16/0427: {with removable and re-insertable liner tubes, e.g. for cleaning}
- A61M 16/0461: {Nasoendotracheal tubes}
- A61M 16/0465: {Tracheostomy tubes; Devices for performing a tracheostomy; Accessories therefor, e.g. masks, filters}
- A61M 16/0488: {Mouthpieces; Means for guiding, securing or introducing the tubes (guiding or introducing with laryngoscopes A61B1/267; holding devices on the body A61M25/02)}
- A61M 16/0666: {Nasal cannulas or tubing (devices for improving normal breathing through the nose A61F5/08; nose filters A62B23/06; outside holding devices A61M25/02)}
- A61M 16/0672: {Nasal cannula assemblies for oxygen therapy}
- A61M 16/085: {Gas sampling}
- A61M 16/0858: {Pressure sampling ports}
- A61M 16/0875: {Connecting tubes}
- A61M 16/10: Preparation of respiratory gases or vapours
- A61M 16/101: {using an oxygen concentrator}
- A61M 16/1095: {in the connecting tubes}
- A61M 16/12: by mixing different gases
- A61M 16/125: {Diluting primary gas with ambient air}
- A61M 16/161: {with means for measuring the humidity}
- A61M 16/204: {used for inhalation control}
- A62B 7/06: with liquid oxygen {or air; Cryogenic systems}
- A62B 7/08: containing chemicals producing oxygen
- A61M 16/0434: {Cuffs}
- A61M 16/208: {Non-controlled one-way valves, e.g. exhalation, check, pop-off non-rebreathing valves}
- A61M 16/209: {Relief valves}
- A61M 2016/0021: {with a proportional output signal, e.g. from a thermistor}
- A61M 2016/0027: {pressure meter}
- A61M 2016/0039: {in the inspiratory circuit}
- A61M 2016/0413: {with detectors of CO2 in exhaled gases}
- A61M 2016/1025: {the O2 concentration}
- A61M 2202/0208: Oxygen
- A61M 2202/025: Helium
- A61M 2202/0275: Nitric oxide [NO]
- A61M 2205/16: with back-up system in case of failure
- A61M 2205/18: with alarm
- A61M 2205/32: with radio-opaque indicia
- A61M 2205/3368: Temperature
- A61M 2205/502: User interfaces, e.g. screens or keyboards
- A61M 2205/70: with testing or calibration facilities
- A61M 2230/202: partial carbon oxide pressure, e.g. partial dioxide pressure (P-CO2)
- A61M 2230/205: partial oxygen pressure (P-O2)
- A61M 2230/432: partial CO2 pressure (P-CO2)
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- A62B: DEVICES, APPARATUS OR METHODS FOR LIFE-SAVING (valves specially adapted for medical use A61M39/00; life-saving devices, apparatus or methods specially adapted for use in water B63C9/00; divers' equipment B63C11/00; specially adopted for use with aircraft, e.g. parachutes, ejector seats, {B64D17/00, B64D25/10}; rescue devices peculiar to mining E21F11/00)

## Abstract

An open system provides breath-synchronized, flow-targeted ventilation to augment respiration by a self-breathing patient. A sensor detects a physical property of a patient's respiratory cycle. A processor monitors the sensor and controls a gas source to deliver oxygen-containing gas through a tube extending into the patient's airway with the flow rate varying over each respiratory cycle in a predetermined non-constant waveform synchronized with the respiratory cycle to augment the patient's spontaneous respiration. Gas is delivered at a flow rate sufficient to significantly mitigate the airway pressure the patient must generate during spontaneous breathing and thereby reduce the patient's work of breathing.

## Claims

### Claim 1

An apparatus for delivering a flow of oxygen-containing gas to the airway of a spontaneously-breathing patient, said apparatus comprising:
a tube delivering a flow of oxygen-containing gas into a patient's airway without interfering with a patient's spontaneous respiration;
a gas source having a housing and delivering a variable flow of gas through the tube combining oxygen from an oxygen source and air from an air source;
a sensor detecting a physical property of a patient's respiratory cycle; and
a processor monitoring the sensor and controlling the gas source to deliver a flow of oxygen-containing gas through the tube to augment the patient's spontaneous respiration, said flow varying over each inspiratory and expiratory phase of the respiratory cycle in a predetermined non-constant flow waveform synchronized with the respiratory cycle, said waveform including:
(a) a positive flow accelerating at the onset of the patient's inspiratory phase at a flow rate sufficient to significantly mitigate the airway pressure the patient must generate during spontaneous breathing and thereby reduce the patient's work of breathing; and
(b) a positive flow during at least the early portion of the patient's expiratory phase at a flow rate sufficient to significantly mitigate the airway pressure the patient must generate during spontaneous breathing and thereby reduce the patient's work of breathing, and to wash carbon dioxide from the patient's airway.

### Claim 2 (depends on 1)

The apparatus of claim 1 wherein the oxygen source comprises an oxygen concentrator within the housing of the gas source.

### Claim 3 (depends on 1)

The apparatus of claim 1 wherein the oxygen source is external to the housing of the gas source.

### Claim 4 (depends on 1)

The apparatus of claim 1 wherein the air source comprises an air compressor within the housing to the gas source.

### Claim 5 (depends on 1)

The apparatus of claim 1 wherein the air source is external to the housing of the gas source.

### Claim 6 (depends on 1)

The apparatus of claim 1 wherein the sensor is attached to a portion of the tube in a patient's airway.

### Claim 7 (depends on 1)

The apparatus of claim 1 further comprising a sampling tube extending along a portion of the tube in a patient's airway to the sensor.

### Claim 8 (depends on 1)

The apparatus of claim 1 wherein the sensor comprises a pressure transducer.

### Claim 9 (depends on 1)

The apparatus of claim 1 wherein the sensor comprises a flow sensor.

### Claim 10 (depends on 1)

The apparatus of claim 1 wherein the sensor comprises a thermistor.

### Claim 11 (depends on 1)

The apparatus of claim 1 wherein the sensor comprises a carbon dioxide sensor.

### Claim 12 (depends on 1)

The apparatus of claim 1 wherein the tube comprises a nasopharyngeal catheter.

### Claim 13 (depends on 1)

The apparatus of claim 1 wherein the tube comprises a cannula.

### Claim 14 (depends on 1)

The apparatus of claim 1 wherein the processor interrupts the flow for a portion of the respiratory cycle.