Treatments involving glutaredoxins and similar agents
AssigneesUniversiteit Maastricht, University of Vermont and State Agricultural College
InventorsYvonne M. Janssen-Heininger, Niki Reynaert, Vikas Anathy, Scott Aesif
Life of this patent
Estimating the term…
Abstract
The present invention generally relates to treatments involving glutaredoxins. In one aspect, systems and methods of the invention can be used to treat a subject having an oxidative stress condition, for example, airway inflammation or asthma. In some embodiments, a glutaredoxin may be used to treat a subject. Also provided in certain aspects of the present invention are kits for therapies involving glutaredoxins, methods for promoting such therapies, and the like.
Claims23
1-26. (canceled)
A method of treating cancer comprising administering to a subject having cancer an effective amount of glutaredoxin to treat the cancer.
28-34. (canceled)
A method, comprising:
- administering, to a subject having or being at risk for a condition characterized by oxidative stress, a composition comprising glutaredoxin,
- wherein the glutaredoxin is GRX1, GRX2, GRX5 or a modified version thereof.
45-46. (canceled)
A kit comprising a container housing GRX1, GRX2, GRX5 or a modified version thereof and instructions for administering components in the kit to a subject having or being at risk for a condition characterized by oxidative stress.
Dependencies are inferred from the claim text.