Autologous cells on a support matrix for tissue repair
OwnerMing Hao ZHENG, Bruno GIANNETTIinventors
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Abstract
The present invention relates to a method for the effective treatment of tissue defects and for tissue regeneration. The method includes seeding autologous cells on a support matrix and implanting the cell-seeded support matrix into a site of transplantation. The present invention also relates to various tissue repair structures that include cells seeded onto a cell-free membrane. The present invention also provides methods for cultivation, seeding, and implantation of autologous cells.
Claims22
A tissue repair structure comprising a support matrix and stem cells;
- wherein said support matrix has a porous surface and a dense surface;
- wherein said stem cells are retained on said porous surface of said support matrix;
- and
- wherein said support matrix is free of intact cells before contact with said stem cells.
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A method for repairing a tissue defect in a patient, said method comprising:
- (a) extracting and isolating cells from said patient;
- (b) seeding said cells onto a cell-free support matrix;
- and
- (c) implanting said support matrix at the site of said tissue defect,
- wherein said cells are selected from the group consisting of tenocytes, stem cells, nerve cells, myocytes, keratinocytes, epithelial cells, and osteocytes.
A method for increasing adipose tissue in a patient, said method comprising:
- (a) extracting and isolating adipocytes from a patient;
- (b) seeding said adipocytes onto a cell-free support matrix;
- and
- (c) implanting said support matrix at a desired site for increased adipose tissue.
Dependencies are inferred from the claim text.