Device For And Method Of Extracting A Fraction From A Biological Sample

A device for isolating a fraction from non-desired material in a biological sample, the fraction being bound to solid phase substrate to define a fraction-bound solid phase substrate, the device comprising:

• an input zone for receiving the biological sample therein;
• a second zone for receiving a fluid therein, the second zone being in fluidic communication with the input zone;
• a constriction interconnecting the input zone and the second zone;
• and
• a force capturing the fraction-bound solid phase substrate and being movable along a path between a first position adjacent the input zone and a second position adjacent the second zone, the force including a source for generating a generally arcuate field extending radially away from the source and being defined by a plurality of forces lines directed towards a trailing edge of the source and towards the path, the plurality of force lines acting to concentrate the fraction-bound solid phase substrate at the trailing edge of the source adjacent the path;
• wherein:
• the force draws the fraction-bound solid phase substrate from the input zone, through the constriction and into the second zone as the force moves from the first position to the second position.

A device for isolating a fraction from non-desired material in a biological sample, the fraction being bound to solid phase substrate to define a fraction-bound solid phase substrate, the device comprising:

• an input zone for receiving the biological sample therein;
• a second zone for receiving a fluid therein, the second zone being in fluidic communication with the input zone;
• a constriction having an input communicating with the input zone and having a cross-sectional area and an output communicating with the second zone and having a cross-sectional area less than the cross-sectional area of the input;
• and
• a force capturing the fraction-bound solid phase substrate and being movable along a path between a first position adjacent the input zone and a second position adjacent the second zone, the force including a source for generating a generally arcuate field extending radially away from the source and being defined by a plurality of forces lines directed towards a trailing edge of the source and towards the path, the plurality of force lines acting to concentrate the fraction-bound solid phase substrate at the trailing edge of the source adjacent the path;
• wherein:
• the force draws the fraction-bound solid phase substrate from the input zone, through the constriction and into the reaction zone as the force moves from the first position to the second position.