Method and device for optical analysis of biopolymer

A biopolymer optical analysis apparatus comprising:

• a biopolymer characteristic analysis chip comprising a solid substrate, at least one channel provided on a surface of the solid substrate and at least one pair of electrically conductive thin films, wherein the pair of the electrically conductive thin films is disposed in a state of being opposed to each other with a certain distance;
• a light source for irradiating the biopolymer with external light;
• an irradiation optical mechanism;
• a light collecting mechanism for collecting a light from the biopolymer;
• a separating component that splits collected light into transmitted light and reflected light at different ratios for each components of the biopolymer;
• an image-forming optical mechanism through which the split lights form images on a detector;
• and
• a two-dimensional detector for detecting the lights forming the images.

A biopolymer characteristic analysis chip comprising:

• a solid substrate;
• at least one channel provided on a surface of the solid substrate, and
• at least one pair of electrically conductive thin films,
• wherein the pair of the electrically conductive thin films is disposed in a state of being opposed to each other with a certain distance;

A biopolymer characteristic analysis method using an optical analysis apparatus comprising:

• a biopolymer characteristic analysis chip comprising a solid substrate, at least one channel provided on a surface of the solid substrate and at least one pair of electrically conductive thin films, wherein the pair of the electrically conductive thin films is disposed in a state of being opposed to each other with a certain distance;
• a light source for irradiating the biopolymer with external light;
• an irradiation optical mechanism;
• a light collecting mechanism for collecting a light from the biopolymer;
• a separating component that splits collected light into transmitted light and reflected light at different ratios for each components of the biopolymer;
• an image-forming optical mechanism through which the split lights form images on a detector;
• and
• a two-dimensional detector for detecting the lights forming the images,
• the method comprising steps of:
• applying external light to the characteristic analysis chip to produce light from a biopolymer;
• splitting the lights by the separating component to detect the lights;
• and
• analyzing characteristics of the biopolymer on the basis of results of detection of the lights.

A biopolymer characteristic analysis method using an optical analysis apparatus comprising:

• a biopolymer characteristic analysis chip comprising a solid substrate, a plurality of nanopores provided in the solid substrate, and an electrically conductive thin film disposed on the solid substrate, wherein at least a portion of the electrically conductive thin film faces the nanopores;
• a light source and an irradiation optical mechanism for producing Raman scattered lights from a biopolymer entering the nanopores;
• a light collecting mechanism for Raman scattered light;
• a separating component that splits collected light into transmitted light and reflected light at different ratios for each components of the biopolymer;
• an image-forming optical mechanism through which the split lights form images on a detector;
• and
• a two-dimensional detector for detecting the lights forming the images,
• the method comprising steps of:
• applying external light to the characteristic analysis chip to produce light from a biopolymer;
• splitting the lights by the separating component to detect the lights;
• and
• analyzing characteristics of the biopolymer on the basis of results of detection of the lights.