Methods for isolating bacteria
AssigneesCentre National De La Recherche Scientifique, Deinove
InventorsJEAN-PAUL LEONETTI, STÉPHANIE TEXIER
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Abstract
The present invention relates to compositions and methods to identify novel bacteria and metabolites derived therefrom. More specifically, the invention describes a novel method to isolate bacteria producing metabolites of interest from environmental samples. Particularly, the invention discloses a method to select rare antibiotic producing bacteria. The invention can be used from any sample and allows the isolation of bacteria having e.g., pharmaceutical or agrochemical interest.
Claims16
A method for producing a drug, comprising (i) culturing, in a suitable medium, a bacterium which naturally produces said drug or an intermediate thereof, (ii) collecting or purifying the drug or intermediate from the culture, and (iii) when an intermediate is produced in step (i), converting said intermediate into said drug, wherein said bacterium is a Deinococcus or a related bacterium.
An improved method for the production of a drug from a cultured microbial cell, the improvement consisting in the use, as said microbial cell, of a Deinococcus or related bacterium.
A method for producing a drug by transformation of a precursor thereof, said method comprising exposing the precursor to a catalyst and collecting the drug resulting from the transformation, wherein the catalyst is a Deinococcus or a related bacterium, or an extract thereof.
A composition comprising a Deinococcus bacterium as an intestinal flora modifier.
Dependencies are inferred from the claim text.