Studying dosimetric impact of motion to generate adaptive patient-specific margins in ebrt planning

A method for generating patient-specific treatment margins, said method comprising:

• receiving a radiation treatment plan (RTP) for irradiating a target over the course of one or more treatment fractions, said RTP including one or more treatment margins around fee target and a planned dose distribution for the target;
• receiving motion data for at least one of the treatment fractions of the RTP;
• calculating a motion-compensated dose distribution for the target using the motion data to adjust the planned dose distribution based on the received motion data;
• and,
• comparing the motion-compensated dose distribution to the planned dose distribution.

A radiation therapy system for irradiating a patient, said system comprising:

• one or more processors programmed to:
• generate a radiation treatment plan (RTF) for irradiating a target over the course of one or more treatment fractions, said RTP including a planned dose distribution to be delivered to the target;
• receive motion data for at least one of the treatment fractions of the RTP;
• calculate a motion-compensated dose distribution for the target using the motion data;
• adjust the planned dose distribution based on dosimetric differences between the motion-compensated dose distribution and fee planned dose distribution;
• and,
• irradiate the patient using the adjusted planned dose distribution.