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US 2014/0005259 A1Published application
Microbicidal and antiparasitic compositions
AssigneeLife Science Investments, Ltd.
InventorsChristian DIEHL, Silvia CHAMI DE DIEHL
Life of this patent
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Abstract
Pharmaceutical or dermo-dermo-cosmetic compositions for topical and intravaginal application for treatment of human and veterinary affections caused by anaerobic organisms or parasites comprising quassinoids or plant extracts containing these phytochemicals, in effective amounts. Such compositions can be administered topically or intravaginally to patients in need thereof in various pharmaceutical dosage forms.
Claims9
A method for treating a condition caused by a parasitic or anaerobic bacterial infection of skin or mucosa, the method comprising:
- administering to a skin or mucus infected by a parasite or an anaerobic bacteria of a human or an animal a therapeutically effective amount of a composition consisting essentially of:
- a. an active agent consisting essentially of at least one quassinoid selected from the group consisting of Brusatol, Ailanthinon, Simalikalactone D, Quassin, Chaparrinone, 15-desacaetylundulatone, 15β-heptylchaparrinone, Neoquassin, Isoquassin, Parain, Quassimarin, Quassinol, Quassol, 18-hydroxy-quassin, Ailantinol A, Ailantinol B, Ailantinol C, Ailantinol D, Ailantinol E, Ailantinol F, Ailantinol G, Bruceanol A, Bruceanol B, Bruceanol C, Bruceanol D, Bruceanol E, Bruceanol F, Bruceanol G, Bruceanol H, Picrasinol A, Picrasinol B, Picrasinol C, Picrasinol D, Bruceoside A, Bruceoside B, Bruceoside C, Picrasinoside A, Picrasinoside B, Picrasinoside C, Picrasinoside D, Picrasinoside E, Picrasinoside F, Picrasinoside G, Picrasinoside H, Eurycomanone, 2-acetylglaucarubine, 13,18-dehydroglaucarubine, Glaucarubinone, Glaucarubine, Holacanthone, 20-simarolide, Simarubolide, Dehydroquassin, Isoparain, Nigakilactone A, Norneoquassin, and Quassialactol;
- and
- b. an optional dermo-cosmetically or pharmaceutically topically acceptable excipient.
1 more element
Dependencies are inferred from the claim text.