Agonists Of Toll Like Receptor For Treating Cardiovasuclar Disease And Obesity
OwnerClaudia Monaco, Marc Feldmanninventors
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Abstract
A method for treating or aiding in preventing cardiovascular disease in a patient, comprising the step of administering to the patient a therapeutically effective amount of an agonist of an endosomal TLR. The agonist of the endosomal TLR may be an agonist of TLR3, optionally poly l:poly C12U or Poly (l:C).
Claims14
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A method for treating or aiding in preventing cardiovascular disease in a patient, comprising the step of administering to the patient a therapeutically effective amount of an agonist of an endosomal TLR.
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A method for treating or aiding in preventing obesity in a patient, comprising the step of administering to the patient a therapeutically effective amount of an agonist of an endosomal TLR.
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A composition or a kit of parts comprising (i) an agonist of an endosomal TLR, and (ii) a lipid lowering drug, an oral or injectable antidiabetic treatment and/or a blood pressure lowering drug and/or an antithrombotic therapy.
A method for selecting a compound expected to be useful in treating or aiding in preventing cardiovascular disease or obesity, the method comprising the step of selecting a compound that is an agonist of an endosomal TLR.
Dependencies are inferred from the claim text.