Family of polyamine arylethylamide compounds, and their cosmetic or dermocosmetic use
AssigneeExsymol
InventorMarie-Christine SEGUIN
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Abstract
The invention relates to a family of stable polyamine arylethylamide compounds, and to the use of these compounds as agents inhibiting DNA damages induced by by-products of the non-enzymatic glycosylation of skin tissues. The invention also relates to cosmetic or dermocosmetic compositions intended to fight skin disorders associated with said glycosylation by-products.
Claims18
A compound represented by the following general formula (II):
- wherein:
- n=1 to 2
- and
- or a pharmaceutically acceptable salt thereof.
A method of preventing or treating skin disorders associated with the formation of non-enzymatic glycosylation by-products or of genotoxic glycotoxins, which comprises administering to a subject in need thereof a compound of general formula (II):
- wherein:
- n=1 to 2
- and
- or a pharmaceutically acceptable salt thereof.
A method of inhibiting DNA damages induced by genotoxic glycotoxins, which comprises administering to a subject in need thereof a compound of general formula (II):
- wherein:
- n=1 to 2
- and
- or a pharmaceutically acceptable salt thereof.
A method of opposing the mutagenic effects of glycotoxins, which comprises administering to a subject in need thereof a compound of general formula (II):
- wherein:
- n=1 to 2
- and
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.