Alfentanil composition for the treatment of acute pain
AssigneeOrexo AB
InventorsAnders Pettersson, Barbro Johansson, Emil Schwan
Life of this patent
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Abstract
There is provided pharmaceutical compositions for the treatment of pain e.g. short-term pain, which compositions comprise a mixture comprising: (a) microparticles of alfentanil, or a pharmaceutically acceptable salt thereof, which microparticles are presented on the surfaces of larger carrier particles; (b) a water-soluble weak base; and (c) a compound which is a weak acid, which acid is presented in intimate mixture with the microparticles of alfentanil or salt thereof. The composition may further comprise a disintegrant. The acid is preferably citric acid.
Claims26
A pharmaceutical composition suitable for sublingual delivery which comprises a mixture comprising:
- (a) microparticles of alfentanil, or a pharmaceutically acceptable salt thereof, which microparticles are presented on the surfaces of larger carrier particles;
- (b) a water-soluble weak base;
- and
- (c) a compound which is a weak acid, which acid is presented in intimate mixture with the microparticles of alfentanil or salt thereof.
Dependencies are inferred from the claim text.