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US 2014/0005117 A1Published application
Compositions and methods for treating aids or cancer by inhibiting the secretion of microparticles
AssigneeMorehouse School of Medicine
InventorsVincent Craig BOND, Michael Powell, Ming Bo Huang, Syed Ali, Andrea D. Raymond, Martin Neville Shelton, Francois Jean Villinger
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Abstract
Novel peptides that inhibit the release of microparticles from cells are disclosed. The peptide contains at least one VGFPV motif at the N-terminal and has a length of 10-100 amino acids. Also disclosed is polynucleotide encoding the peptide, expression vectors carrying the polynucleotide, and methods for treating AIDS and tumors using the novel peptides.
Claims32
1-29. (canceled)
A peptide for inhibiting the release of microparticles in a cell, comprising:
- a N-terminal;
- a C-terminal;
- and
- at least two VGFPV (SEQ ID NO:
- 1) motifs.
2 more elements
Dependencies are inferred from the claim text.