Treatment of disorders with altered vascular barrier function
AssigneeGenentech, Inc.
InventorsWeilan Ye, Leon H. Parker, IV, Christopher W. Wilson
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Abstract
The present invention provides methods of using RASIP1 agonists and antagonists to modulate vascular barrier function and regulate new vessel formation, and to treat related disorders.
Claims10
A method of treating a disorder associated with altered vascular barrier function in a subject comprising administering to the subject a RASIP1 modulator.
A method of reducing or inhibiting vascular barrier function in a subject in need thereof, comprising administering to the subject a RASIP1 agonist.
A method of increasing or enhancing vascular barrier function in a subject in need thereof, comprising administering to the subject a RASIP1 antagonist.
A method of treating a disorder that requires new vessel formation in a subject comprising administering to the subject a RASIP 1 inhibitor.
Dependencies are inferred from the claim text.