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US 2014/0005112 A1Published application
Method of treating chronic heart failure by administering relaxin
OwnerElaine Unemori, Sam Teichman +3inventors
InventorsElaine Unemori, Sam Teichman, Thomas Dschietzig, Dennis R. Stewart, Martha Jo Whitehouse
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Abstract
The present disclosure relates to methods for treating human subjects afflicted with chronic heart failure. The methods described herein employ administration of relaxin.
Claims17
A method of treating compensated chronic heart failure comprising
- (a) selecting a human subject with compensated chronic heart failure and
- (b) administering a pharmaceutically active H2 relaxin in an amount effective to reduce the frequency of decompensation to acute heart failure
- wherein the administration of H2 relaxin maintains the subject in a compensated state.
A method of treating compensated chronic heart failure comprising
- (a) selecting a human subject with compensated chronic heart failure and
- (b) administering a pharmaceutically active H2 relaxin in an amount effective to improve the functional capacity of the subject
- wherein the administration of H2 relaxin reduces the frequency of decompensation episodes.
Dependencies are inferred from the claim text.