Composition for aggregating biological sample

A method for preparing paraffin block comprisings:

• centrifuging a fixed biological sample, removing the supernatant, and then obtaining the sample sediment;
• adding the first composite comprising at least one water-soluble polymer selected from the group comprising polyvinyl alcohol, polyethylene oxide, polyacrylamide, polyvinylpyrrolidon, polyacrylic acid, polyethyleneimine, polyamines, polyamideamine, and polydiallyldimethylammonium chloride and distilled water to the sediment to prepare the first sample solution;
• adding the second composite comprising at least one organic solvent selected from the group consisting of alcohol, xylene, and acetone and at least one medical adhesive selected from the group consisting of cyanoacrylate, fibrin glue, protein glue, polyurethane, and sealant containing PEG (polyethylene glycol) to the first sample solution to prepare the second sample solution;
• centrifuging the second sample solution, removing the supernatant, and then obtaining the aggregated sample sediment;
• and
• subjecting the aggregated sample sediment to the spontaneous infiltration process to prepare the paraffin block.

A method for preparing a cell block sample for cellular microarray comprising:

• 1) recovering the different cellular samples to be observed and fixing them;
• 2) treating an organic solvent containing a medical adhesive and a water soluble solution containing a water-soluble polymer to the fixed cell sediment to obtain the cell aggregate;
• 3) embedding the cell aggregate to obtain a cell block;
• 4) stamping out the embedded cell pellets from the cell block and arraying them in a fixed frame;
• and
• 5) making the arrayed frame to a block or a section.