Method for detecting risk of progression of low grade cervical dysplasia
AssigneeThe USA, as represented by the Secretary, Dept. of Health and Human Services
InventorsThomas Ried, Kerstin Heselmeyer-Haddad, Winfried Steinberg, Gert Auer, Sonia Andersson, Catharina Larsson
Life of this patent
Estimating the term…
Abstract
The invention provides methods for identifying conditions of low grade cervical dysplasia and assessing the progressive potential of individual lesions to develop into high grade cervical dysplasia and cervical squamous cell cancer as well as cervical adenocarcinoma.
Claims24
1-16. (canceled)
A kit for assessing a change in a patient condition of low grade cervical dysplasia to a condition of high grade cervical dysplasia comprising a probe for detecting a genomic amplification of chromosome 3q and instructions for using the probe to assess the change in a patient condition of low grade cervical dysplasia to a condition of high grade cervical dysplasia in accordance with a method of any of claims 1-16.
A method for identifying a patient at risk of developing invasive cervical carcinoma, comprising:
- making a first identification of a genomic amplification of chromosome 3q in a sample obtained from a patient known to have had a condition of either
- i) low grade cervical dysplasia;
- or
- ii) no dysplasia
- thereby identifying a patient at risk of developing invasive cervical carcinoma.
29-63. (canceled)
65-67. (canceled)
A method of diagnosing adenocarcinoma in a subject comprising:
- detecting genomic amplification of a telomerase gene or portion thereof in a subject.
75-76. (canceled)
Dependencies are inferred from the claim text.