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US 2014/0004544 A1Published application
Fen1 as a marker for chronic obstructive pulmonary disease (copd)
AssigneeRoche Diagnostics Operations, Inc.
InventorsJohann Karl, Julia Riedlinger, Norbert Wild
Life of this patent
Estimating the term…
Abstract
An in vitro method aiding in the assessment of chronic obstructive pulmonary disease (COPD). The disclosure further relates to a method for assessing COPD from a sample, derived from an individual, by measuring the protein FEN1 in said sample in vitro.
Claims18
An in vitro method for diagnosing chronic obstructive pulmonary disease (COPD) in a patient, comprising:
- determining a concentration of protein FEN1 in a serum, plasma, or whole blood sample obtained from the patient;
- comparing the concentration of protein FEN1 in the sample determined in said step of determining with a protein FEN1 reference concentration;
- providing a diagnosis of COPD in the patient if the concentration of protein FEN1 in the sample determined in said step of determining is greater than the protein FEN1 reference concentration.
An in vitro method for differentiating between asthma and chronic obstructive pulmonary disease (COPD) in a patient suspected of having asthma, comprising:
- determining a concentration of protein FEN1 in a serum, plasma, or whole blood sample obtained from the patient;
- comparing the concentration of protein FEN1 in the sample determined in said step of determining with a protein FEN1 reference concentration;
- providing a diagnosis of COPD if the concentration of protein FEN1 in the sample determined in said step of determining is greater than the protein FEN1 reference concentration.
Dependencies are inferred from the claim text.