Biosurface engineering
OwnerNicolai Vladimirovich Bovin, Andrey Alfredovich Formanovsky +3inventors
InventorsNicolai Vladimirovich Bovin, Andrey Alfredovich Formanovsky, Stephen Micheal Henry, Stephen Robert Parker, Inna Stanislavovna Popova
Life of this patent
Estimating the term…
Abstract
The invention relates to methods of localizing biofunctional moieties (F) to surfaces and synthetic constructs of the general structure F-S-S′ for use in such methods. F is the biofunctional moiety, S is a spacer covalently linking F to S′, and S′ is sterol. In particular, the invention relates to the preparation of biofunctional surfaces and surface modified biological structures including cells (kodecytes), enveloped viruses (kodevirions) and liposomes or virosomes (kodesomes).
Claims25
1-38. (canceled)
A method of localizing a hydrophilic biofunctional moiety (F) to a surface comprising the step of contacting the surface with an aqueous solution of a water dispersible construct of the structure F-S-S′ where F is the biofunctional moiety, S is a spacer covalently linking F to S′, and S′ is steryl.
Dependencies are inferred from the claim text.